National Projects

Novel antibody-drug conjugates against Pseudomonas aeruginosa and Burkholderia cepacia complex infections: Proof of concept

Oligo4Resistance: New approach to improve antifungal efficacy in pathogenic Candida species based on antisense therapy

Deciphering Burkholderia cepacia Complex Small RNAs: Insights into Antibiotic Resistance Control and Therapeutic Potential

Bioengineering to Advance Personalized Therapies for Aplastic Anemia

Engineering advanced colorectal cancer ecosystems to evaluate tumour-microbiome dynamics in vitro

From chitin degradation to natural products: leveraging marine microbiomes for the circular blue bioeconomy

New strategies for sustainable production of cell-based fish

Institute for Health and Bioeconomy

Instituto de Bioengenharia e Biociências - EQUIPAR +2

Instituto de Bioengenharia e Biociências- Plurianual

iBB Equipamento

Scaling up sustainable mackerel cell production for cellular agriculture

Biomanufacturing of DNA-origami nanostructures for image-guided drug delivery

3rd generation oral vaccines against photobacteriosis in fish farming

Microbiome-Guided Solutions Against Emerging Pathogens in Octocorals: Enhancing Host Health and Resilience to Climate Change

Blue Bioeconomy Pact

Economic valorization of the invasive alga Rugulopteryx okamurae using a circularity approach

Development of starter yeasts for the production of sustainably preserved stylistic wines

Untangling the critical drivers for tau phase separation with RNA and RNA-binding proteins in Tauopathies

Extraction of functional and bioactive compounds from subproducts of tomato processing and valorization of them into potential biomedical applications, edible films and packaging

Decoding Epigenetic Disease Signatures in Twins Discordant for Systemic Lupus Erythematosus

Mechanistic insights into adaptation and increased robustness to acetic acid and other weak acids toxicity in yeasts

Investigation of the molecular mechanisms involved in the inactivation of the X chromosome in human embryonic stem cells

Reversal of X-chromosome inactivation during naïve human iPSC reprogramming

Seaweed biorefinery for the upgrade of carbohydrates to sustainable bioplastics

Magnetic-responsive perfusable 3D tissue scaffolds for vascularization studies

BioData.pt - Infraestructura Portuguesa de Dados Biológicos

Deciphering the mechanisms of transcriptional regulation that control antifungal drug resistance in the pathogenic yeast candida glabrata: aiming the development of improved diagnosis and therapeutic approaches

Upscaling the Production of Human Pluripotent Stem Cell-derived Cardiomyocytes using Vertical-Wheel Bioreactors

Biorecognition as a Tool for the Functionalization of Cellulose-based Materials with Biomolecules and Nanostructures

Generation of gene-edited cerebellar organoids for ataxia research

Harnessing the Catalysti power of Host microbe interactions

The coding and noncoding virulome of Burkholderia cenocepacia

Functionalised nanoparticles for enrichment and detection of SARS-CoV-2 in clinical and environmental samples

Pseudozyma spp based biorefinery: Membrane bioreactors for production of aviation fuel and biosurfactants for bioremediation

Activating Dormant Bacteria with phage-derived proteins to enhance antibiotic efficacy

Nanomateriais com Fluorescencia Atrasada para Sistemas de Imagiologia e Detecção

Next generation of antibiofilm agents: Multivalent dendrimers with antimicrobial and biofilm disruption activity

Matriz extracelular descelularizada como componente fundamental no fabrico de scaffolds hierárquicos e biomiméticos para regeneração de tecidos periodontais funcionais

Dendrímeros Inteligentes para Nanoteranóstica do Cancro

Wirelessly activated multifunctional nanobioelectronics to enable novel oncological therapies

Molecular and Mechanical Forces in Biology measured with Force Feedback Microscopy

The use of Escherichia coli biofilms for the production of recombinant proteins and other added-value compounds

Análise estrutural e funcional do factor de transcrição Haa1 indispensável na resposta e resistência da levedura a ácido acétic

Design and operation of a prototype packed-bed reactor for the production of hematopoietic stem/progenitor cells

Modelos in silico que orientam a estimulação biofísica in vitro de scaffolds hierárquicos biomiméticos: uma abordagem de modelação computacional visando a regeneração osteocondral funcional

Explorando a interferência probiótica entre lactobacilos e Candida para potenciar o desenvolvimento de novas terapias antifúngicas

Lactic acid bacteria as cell factories: Synthetic Biology approach for plasmid DNA and recombinant protein production

Development of a Lateral Flow Assay working prototype for detection of antibodies to SARS-CoV-2

The role of the plasma membrane in the unconventional secretion of tau: insights into the progression of tauopathies

Marine oil spills: Green biological Emulsifiers agents production and autonomous Robotic tools for response optimization

Exploiting the healing capacity of nature´s microbiomes for improved fish larviculture

Harnessing the power of the microbial metamobilome: using marine sponges as models to uncover novel biotechnological appliances from symbiont communities

Organoid Engineering for Production of 3D Cardiovascular Microtissues from Human Induced Pluripotent Stem Cells for Cardiotoxicity Assays

Targeting pathogenesis and engineering cell factories: developing mixed regulatory-metabolic genomic models in yeasts

Biobased Fuels

Impact of engineered nanoparticles and microplastics on textile wastewater treatment with aerobic granular sludge technology

Development of an innervated heart organoid: The first step towards modulating the dialogue between the brain and the heart

Development of a scalable manufacturing process for therapeutic human mesenchymal stem/stromal cell-derived exosomes

Electrically conductive platforms for neural stem cell culture and differentiation

Quality by design-centered platform for the manufacturing of CAR-engineered NK cells and extracellular vesicles for immunotherapy

Desenvolvimento e aplicação de nanomagnetes e ferrofluidos com variação on-to-off da magnetização em torno da temperatura ambiente

Optimization of stimuli in bi-tissue scaffolds: from mathematical and computational modeling to experimental validation

Integrated optical strategies for advanced Lab on Chip biosensors

Cell penetrating p28 peptide-mediated delivery of nanomedicines for cancer treatment

Bacteriófagos no Diagnóstico e Prevenção de Infeções Multiresistentes em Portugal e no Mundo

Development of an Innovative Collector and Protocol for the Purification of Apitoxin for Use in the Pharmaceutical and Cosmetic Industries

Precision oncology by innovative therapies and technologies

Portuguese Platform of BioImaging

Accelerating progress toward the new era of precision medicine

Multimodal chromatography as an alternative to pure chromatographic modes for the capture and polishing of antibody streams

Innovative and efficient platforms for removing genotoxic impurities

Engineering of Smart Exosomes for Amyloid-beta Clearance in Alzheimer disease

The aggregation-prone structures of Huntingtin exon 1 at the single-molecule level: Influence of membranes and implications in Huntington disease

New technologies and strategies for stem cell manufacturing bioprocess monitoring and artificial intelligence-based modeling

Smart Valorization of Macroalgae

Smarter wine fermentations: integrating Omics-tools for development of novel mixed-starter cultures for tailor-made wine production

Are non-coding RNAs contained in Burkholderia cepacia complex extracellular vesicles used to manipulate the host's immune response?

Stimuli optimization for BioScaffolds: from numerical modelling to in vitro tests

Sustainable Production of Bioactive Metabolites from Microbial Symbionts of Marine Sponges and Corals

Biotechnological valorization of the wilde type plant Tramazeira

Urease next-generation inhibition therapy