A new project approved under the 2025 ๐๐๐๐๐๐ ๐๐ฉ๐๐ง ๐๐๐ฅ๐ฅ – ๐๐๐ฅ๐ฅ๐ฎ๐ฅ๐๐ซ ๐๐ง๐ ๐๐จ๐ฅ๐๐๐ฎ๐ฅ๐๐ซ ๐๐๐ฌ๐๐๐ซ๐๐ก, is now underway, addressing a critical gap in how FRET data for ๐ข๐ง๐ญ๐ซ๐ข๐ง๐ฌ๐ข๐๐๐ฅ๐ฅ๐ฒ ๐๐ข๐ฌ๐จ๐ซ๐๐๐ซ๐๐ ๐ฉ๐ซ๐จ๐ญ๐๐ข๐ง๐ฌ is curated, shared, and reused.
๐๐ก๐ฒ ๐ข๐ญ ๐ฆ๐๐ญ๐ญ๐๐ซ๐ฌ
FRET has emerged as a powerful technique in โdynamic structural biologyโ to probe the conformational ensemble and molecular interactions of ๐๐ง๐ญ๐ซ๐ข๐ง๐ฌ๐ข๐๐๐ฅ๐ฅ๐ฒ ๐๐ข๐ฌ๐จ๐ซ๐๐๐ซ๐๐ ๐๐ซ๐จ๐ญ๐๐ข๐ง๐ฌ (IDPs).
The project brings together complementary expertise to develop a FAIR-compliant community resource for ๐
๐๐๐ ๐๐๐ญ๐, including a central dataset registry and a MIADE-FRET reporting standard, enabling reproducibility, comparability, and ML-ready datasets in structural biology.
๐ ๐๐จ๐ฅ๐ฅ๐๐๐จ๐ซ๐๐ญ๐ข๐ฏ๐ ๐๐๐๐๐๐ ๐๐๐๐จ๐ซ๐ญ
Managed through ELIXIR Portugal (BioData.pt) and coordinated by Ana M. Melo, the project integrates expertise from Eรถtvรถs Lorรกnd University (Gรกbor Erdลs) and the Universitร degli Studi di Padova (Maria Cristina Aspromonte) to shape data standards, validation workflows, and community adoption.
By strengthening FAIR data practices, this initiative will ๐๐ฆ๐ฉ๐จ๐ฐ๐๐ซ ๐ฆ๐จ๐ซ๐ ๐ซ๐จ๐๐ฎ๐ฌ๐ญ, ๐ข๐ง๐ญ๐๐ ๐ซ๐๐ญ๐ข๐ฏ๐, ๐๐ง๐ ๐๐๐ญ๐-๐๐ซ๐ข๐ฏ๐๐ง ๐ซ๐๐ฌ๐๐๐ซ๐๐ก ๐ข๐ง ๐ฌ๐ญ๐ซ๐ฎ๐๐ญ๐ฎ๐ซ๐๐ฅ ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ.