William Salvador

William Sousa Salvador

PhD Student

HKK-4636-2023

Web of Science profile

iBB Group: scerg

william.salvador@tecnico.ulisboa.pt

Expertise: Bioprocess economic modeling, Bioprocess design, Stirred-tank bioreactors, Human induced pluripotent stem cells, Extracellular vesicles

Short Bio:

William Salvador is a PhD student in the field of bioengineering, focused on the development of novel production strategies for human induced pluripotent stem cells (hiPSCs) and their derivatives. He holds an MSc in Biomedical Engineering from NOVA School of Science and Technology and is undertaking his PhD at Instituto Superior Técnico of the University of Lisbon. By combining bioprocess economic modeling and bioreactor-based stem cell culture, he seeks to develop large-scale and cost-efficient methods for the expansion of hiPSCs and the production of hiPSC-derived extracellular vesicles, which will help bring their therapeutic applications closer to routine clinical practice.

ORCID

SCOPUS

CIÊNCIA VITAE

Research Focus:

Application of bioprocess economic modeling and bioreactors to the large-scale and cost-efficient production of human induced pluripotent stem cells and their derivatives.

SMART: New technologies and strategies for stem cell manufacturing bioprocess monitoring and artificial intelligence-based modeling (PTDC/EQU-EQU/3853/2020)
VitaminSea: Enhancing cost-effective and efficient nutrient delivery in fish embryonic stem cell culture medium via functional bioactive microcarriers (22-CM-PT-DG-1-317)

Salvador, W. O. S., Nogueira, D. E. S., Ferreira, F. C., Cabral, J. M. S., & Rodrigues, C. A. V. (2023). BEMSCA: a novel decision support tool applied to the optimal design of a large-scale human induced pluripotent stem cell expansion bioprocess. Current Research in Biotechnology, 6, 100163. https://doi.org/10.1016/j.crbiot.2023.100163

Salvador, W. O. S., Nogueira, D. E. S., Bovolato, A. L. C., Ferreira, F. C., Cabral, J. M. S., & Rodrigues, C. A. V. (2023). Bringing cellular agriculture to the table: the role of animal cell bioreactors. In E. D. G. Fraser, D. L. Kaplan, L. Newman, & R. Y. Yada (Eds.), Cellular agriculture: technology, society, sustainability and science (pp. 161–175). Academic Press.

Salvador, W. O. S., Ribeiro, I. A. B., Nogueira, D. E. S., Ferreira, F. C., Cabral, J. M. S., & Rodrigues, C. A. V. (2022). Bioprocess economic modeling: decision support tools for the development of stem cell therapy products. Bioengineering, 9(12), 791. https://doi.org/10.3390/bioengineering9120791

iBB People

William Sousa Salvador