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    • Mission & Goals
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    • Contact us
  • People
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  • Research
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      • Bioprocess Engineering
      • Biological Sciences
      • Biocatalysis and Biotransformation
      • Biospectroscopy and Interfaces
      • Stem Cell Engineering
    • Publications
      • Peer-reviewed publications
      • Books & Book Chapters
      • PhD Theses
      • Oral communications
    • Funded Projects
      • National Projects
      • International Projects
  • Innovation
    • Bridging Innovation and Industry
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Sofia Duarte

Sofia Oliveira Dias Duarte

assistant researcher
ITU-8370-2023
Web of Science profile
iBB Group: berg
sofia.duarte@tecnico.ulisboa.pt
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Expertise: NanotechnologyDrug delivery systemsSynthetic BiologyGenome editingLactic Acid Bacteria
Short Bio:
Sofia Duarte earned her PhD from Instituto Superior Técnico (IST), with her thesis on using synthetic biology in Lactic Acid Bacteria. She also holds a Master's in Applied Microbiology and a degree in Biology (Molecular Biology and Genetics), both from Faculdade de Ciências da Universidade de Lisboa.Currently, as a Post-Doctoral Researcher at IST, Sofia focuses on nanotechnology in biomedical and bioengineering applications. She's leading innovative projects in nanoparticle-based drug delivery systems for diseases like diabetes and type-2 inflammation. Previously, she contributed significantly to bacteriophage production for pre-clinical trials, specializing in purification techniques and endotoxin removal.
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Research Focus:
Develop and apply nanotechnology-based approaches for biomedical and bioengineering applications.

LactoSynt: Lactic Acid Bacteria as Cell Factories: a Synthetic Biology Approach for Plasmid DNA and Recombinant Protein Production (PTDC/BTM-SAL/28624/2017)

A Synthetic Biology based approach to construct a Lactic Acid Bacteria/artificial plasmid platform for the production of plasmid DNA and recombinant proteins (UID/BIO/04565/2013)

SYNBIOBACTHER: Synthetic biology approaches to engineer “therapeutic” bacteria (PTDC/EBB-BIO/102863/2008)

Kumar, M., Virmani, T., Kumar, G., Deshmukh, R., Sharma, A., Duarte, S., Brandão, P. & Fonte, P. (2023). Nanocarriers in Tuberculosis Treatment: Challenges and Delivery Strategies. Pharmaceuticals, 16(10), 1360.

Viegas, C., Patrício, A. B., Prata, J., Fonseca, L., Macedo, A. S., Duarte, S. O., & Fonte, P. (2023). Advances in Pancreatic Cancer Treatment by Nano-Based Drug Delivery Systems. Pharmaceutics, 15(9), 2363.

Monteiro, G. A., & Duarte, S. O. (2022). The Effect of Recombinant Protein Production in Lactococcus lactis Transcriptome and Proteome. Microorganisms, 10(2), 267.

Duarte, S. O., & Monteiro, G. A. (2021). Plasmid replicons for the production of pharmaceutical-grade pDNA, proteins and antigens by Lactococcus lactis cell factories. International Journal of Molecular Sciences, 22(3), 1379.

Duarte, S. O., Martins, M. C., Andrade, S. M., Prazeres, D. M., & Monteiro, G. A. (2019). Plasmid Copy Number of pTRKH3 in Lactococcus lactis is Increased by Modification of the repDE Ribosome‐Binding Site. Biotechnology Journal, 14(8), 1800587.

About

iBB aims to excel in research and advanced education in biotechnology, by responding to the challenge of exploring innovative approaches to key scientific and technological questions in Biosciences and Bioengineering and of transforming scientific knowledge into tangible innovation.

Contacts

Técnico Lisboa
Av. Rovisco Pais
1049-001 Lisboa, Portugal

+351 218 419 065
ibb@ibb.pt

Associate Laboratory

Institute for Health and Bioeconomy (i4HB)

Projects funded by:

iBB Funding: FCT / Portuguese Republic / EU / Portugal 2020 / PRR

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