Raquel Barros

Raquel Aires Barros

full professor

E-6021-2010

Web of Science profile

iBB Group: berg

rabarros@tecnico.ulisboa.pt

Expertise: Downstream Processing, Aqueous Two-Phase Systems, purification biopharmaceuticals, microfluidic systems

Short Bio:

Raquel Aires Barros is a dedicated research focus on the field of Bioprocessing Engineering, a multidisciplinary field at the intersection of biology, engineering, and technology. With a Master in Biotechnology and a PhD in Chemical Engineering (1990), Raquel´s work aims to the development of sustainable bioprocessing for production of biological products, contributing to educe environmental footprints, increase productivity, improve (bio)product quality and drastically reduce manufacturing costs.Current research interests include the development of continuos separation processes with high performance and efficiency for purification biopharmaceuticals, with special emphasis on the purification of antibodies and the development of devices- "Lab-on-a-Chip" - for protein purification / separation of cells in the microscale using microfluidic devices.

ORCID

SCOPUS

CIÊNCIA VITAE

Research Focus:

Investigation of new separation processes for purification of biopharmaceuticals

CODOBIO- Continuous Downstream Processing of Bioproducts. , MARIE SKŁODOWSKA-CURIE ACTIONS ,Innovative Training Networks (ITN) Call: H2020-MSCA-ITN-2017
INTENSO -Gaining Productivity, Cost Efficiency and Sustainability in the Downstream Processing of Bio-Products by novel Integration and Intensification strategies” (FP7-KBBE-2012-6 – single stage) http://dx.doi.org/10.13039/501100000780

AIMS- Advanced Interactive Materials by Design”, SIXTH FRAMEWORK PROGRAMME; PRIORITY 3,NMP3-CT2004-500160
http://dx.doi.org/10.13039/501100000780

Malik Abdul Wahab, C. Domingues, Ana M. Azevedo, Virginia Chu,Joao Pedro Conde, M. Raquel Aires-Barros (2024). An integrated microfluidic device for continuous bioprocessing. Separation and Purification Technology, 332, 125702.
https://doi.org/10.1016/j.seppur.2023.125702

Ricardo Fradique; Andreia Jardim; Ana M Azevedo; Virginia Chu; João P Conde; M Raquel Aires‐Barros (2023). Continuous microfluidic platform combining cell lysis and protein extraction for screening overall process conditions. Journal of Chemical Technology & Biotechnology.
https://doi.org/10.1002/jctb.7564

Ferreira-Faria, D., Domingos-Moreira, F., Aires-Barros, M. R., Ferreira, A., Azevedo, A. M., “Continuous precipitation of antibodies using oscillatory flow reactor” (2023), Sep. Pur. Technol. , 317,123924.
https://doi.org/10.1016/j.seppur.2023.123924

Jacinto, M.J.; Wagner, Alexandra; Sá, Inês M.; Patinha, David J.S.; Marrucho, Isabel M.; Gonçalves, João; Willson, Richard C.; Azevedo, A.M.; Aires-Barros, M.R. (2021) Screening polymeric ionic liquids for chromatography-based purification of bacteriophage M13, Sep. Pur. Technol. 257, 117906.
https://doi.org/10.1016/j.seppur.2020.117906

Ferreira-Faria, D.; Aires-Barros, M.R.; Azevedo, A.M. (2020).Continuous aqueous two-phase extraction: From microfluidics to integrated biomanufacturing. Fluid Phase Equilibria, 508, 112438.
https://doi.org/10.1016/j.fluid.2019.112438

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Raquel Aires Barros