Paulo Jorge Dias

assistant researcher

K-6268-2012

Web of Science profile

iBB Group: bsrg

pjdias@tecnico.ulisboa.pt

Expertise: Yeast Molecular Biology and PhysiologyComparative Genomics and PangenomicsSystems BiologyBioinformaticsEvolution of Genes and Genomes

Short Bio:

PJ Dias graduated in Microbial Biology and Genetics from the Faculty of Sciences of the University of Lisbon in 2001. Subsequently, PJ Dias pursued a Master’s post-graduation in Probability and Statistics at the same institution, successfully completing it with the highest classification. In 2010, PJ Dias earned his PhD in Biotechnology from Instituto Superior Técnico (IST), University of Lisbon, with distinction. In the past 17 years, PJ Dias has been a member of the Biological Sciences Research Group (BSRG) at the Institute for Bioengineering and Biosciences (iBB) and, more recently, at the Institute for Health and Bioeconomy (i4HB).

Research Focus:

Investigation on Comparative Genomics and Pangenomics, Systems Biology and Bioinformatics focusing to understand the Evolution and Bioengineering of Microorganisms, in particular, hemiascomycete yeasts.

3rd edition of Advanced Computing Projects: A0 Experimental Access (round B), 2023 (Contract: 2022.42199.CPCA.A0)

3rd edition of Advanced Computing Projects: A1 Preparatory or Development Access (round C), 2023 (Contract: 2023.05807.CPCA.A1)

Lactosynt – Lactic acid bacteria as cell factories: a Synthetic Biology approach for plasmid DNA and recombinant protein production (Contract: PTDC/BTM-SAL/28624/2017)

YEASTPEC – Engineering of the yeast Saccharomyces cerevisiae for bioconversion of pectin- containing agro-industrial side-streams (Contract: ERA-IB-2/0003/2015)

Major Facilitator Superfamily transporters in the context of modern agriculture constraints: exploratory studies (Contract: EXPL/AGR-PRO/1013/2013)

Oral presentations in International Meeting: Dias PJ, Santos JM, Antunes DL, Duarte SO, Moreira LM, Monteiro GA, Graph-based and Gene-based Pangenome of Lactococcus lactis and Lactococcus cremoris, CSHL Genome Informatics Conference, Cold Spring Harbour Laboratory, 6-9th December, 2023 https://youtu.be/vYr-alXOHEM

Dinis Martins, Gene-based and Graph-based Pangenomes of 8 Burkholderia Species: Construction, Visualization and Analysis, Master of Science in Biological Engineering, University of Lisbon, 2023 (thesis under the supervision of Dr. PJ Dias).

Godinho CP, Dias PJ, Ponrot E, Sá-Correia I, (2018). The paralogous genes PDR18 and SNQ2, encoding ABC multidrug resistance trnsporters, derive from a recent duplication event, PDR18 being specific of the Saccharomyces genus. Frontiers in Genetics. 9: 476.

Palma M, Dias PJ, Roque FC, Luzia L, Guerreiro JF, Sá-Correia I (2017). The Zygosaccha- romyces bailii transcription factor Haa1 is required for acetic acid and copper stress responses suggesting subfunctionalization of the ancestral bifunctional protein Haa1/Cup2. BMC Genomics. 8: 75.

Dias PJ, Sá-Correia I (2014). Phylogenetic and syntenic analyses of the 12-spanner drug:H+ antiporter family 1 (DHA1) in pathogenic Candida species: evolution of MDR1 and FLU1 genes. Genomics. 104: 45-57.

iBB People

Paulo Jorge Dias