Fábio Fernandes

assistant professor

J-6358-2012

Web of Science profile

iBB Group: bsirg

fernandesf@tecnico.ulisboa.pt

Expertise: Membrane Biophysics, Fluorescence Imaging, FRET, FRET imaging,

Short Bio:

Fábio Fernandes concluded his PhD in Chemistry at the Instituto Superior Técnico (IST) in 2007, working on the topic of protein-lipid interactions. He then carried out consecutive postdocs while working in the field of Membrane Biophysics (Max-Plack Institute in Göttingen and at IST), finally joining UCIBIO as an Auxiliary Researcher in 2016. In 2017, Fábio Fernandes returned to IST as an FCT Researcher and since 2019 he is Assistant Professor at the Department of Bioengineering of IST. His research is in the field of Molecular and Cellular Biophysics, with focus on probing Biomembrane organization through advanced Fluorescence imaging and Spectroscopy.

Research Focus:

Cellular Biophysics and Membrane Organization

SENTINELEVs: Engineering broad-spectrum defensosomes for a bacterial antivirulence therapeutic strategy (EXPL/BTM-MAT/0910/2021)
NEUROAbetaCLEAR: Engineering of Smart Exosomes for Amyloid-beta Clearance in Alzheimer disease (PTDC/BTM-SAL/31057/2017)

Structural determinants for compartmentalization of phosphoinositides: From nanoscale molecular organization to cellular events (IF/00386/2015/CP1272/CT0010)

Sarmento, M. J., & Fernandes, F. (2023). Choosing the Right Fluorescent Probe (pp. 1–49). Springer International Publishing. https://doi.org/10.1007/4243_2022_30

Gonçalves, D., Pinto, S. N., & Fernandes, F. (2023). Extracellular Vesicles and Infection: From Hijacked Machinery to Therapeutic Tools. Pharmaceutics, 15(6), 1738. https://doi.org/10.3390/pharmaceutics15061738

Borges-Araújo, L., Monteiro, M. E., Mil-Homens, D., Bernardes, N., Sarmento, M. J., Coutinho, A., Prieto, M., & Fernandes, F. (2022). Impact of Ca2+-Induced PI(4,5)P2 Clusters on PH-YFP Organization and Protein-Protein Interactions. Biomolecules, 12(7), 912. https://doi.org/10.3390/biom12070912

Borges-Araújo, L., Domingues, M. M., Fedorov, A., Santos, N. C., Melo, M. N., & Fernandes, F. (2021). Acyl-chain saturation regulates the order of phosphatidylinositol 4,5-bisphosphate nanodomains. Communications Chemistry, 4(1), 164. https://doi.org/10.1038/s42004-021-00603-1

Sarmento, M. J., Borges-Araújo, L., Pinto, S. N., Bernardes, N., Ricardo, J. C., Coutinho, A., Prieto, M., & Fernandes, F. (2021). Quantitative FRET Microscopy Reveals a Crucial Role of Cytoskeleton in Promoting PI(4,5)P2 Confinement. International Journal of Molecular Sciences, 22(21), 11727. https://doi.org/10.3390/ijms222111727

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Fábio Fernandes