Cristiana Ulpiano

Cristiana Silva Ulpiano

PhD Student

GFQ-9868-2022

cristiana.ulpiano@tecnico.ulisboa.pt

Expertise: Mesenchymal stromal cells, Extracellular vesicles, Stirred-tank bioreactors, Genetic engineering, Minicircle vectors

Short Bio:

Cristiana da Silva Ulpiano is a final-year PhD student specializing in Biotechnology and Biosciences. She holds a BSc in Molecular and Cellular Biology from NOVA School of Science and Technology and an MSc in Biotechnology from Instituto Superior Técnico of the University of Lisbon. Her work is focused on engineering mesenchymal stromal cell-derived extracellular vesicles using RNAi-expressing minicircles, with the purpose of developing a novel cell-free therapeutic approach for angiogenic disorders characterized by vascular overgrowth.

ORCID

SCOPUS

CIÊNCIA VITAE

Research Focus:

Genetic engineering of mesenchymal stromal cell-derived extracellular vesicles using minicircle vectors envisioning a novel anti-angiogenesis therapy

Ulpiano, C., da Silva, C.L., & Monteiro, G.A. (2023). Bioengineered Mesenchymal-Stromal-Cell-Derived Extracellular Vesicles as an Improved Drug Delivery System: Methods and Applications. Biomedicines, 11(4), 1231. doi: 10.3390/biomedicines11041231.

Ulpiano, C., da Silva, C.L., & Monteiro, G.A. (2021). Mesenchymal Stromal Cells (MSCs): A Promising Tool for Cell-Based Angiogenic Therapy. Current Gene Therapy, 21(5), pp. 382–405. doi:10.2174/1566523221666210917114353.

Silva, M., Ulpiano, C., Bernardes, N., Monteiro, G.A., & da Silva, C.L. (2019). Gene delivery as a tool to improve the therapeutic features of mesenchymal stromal cells: methods and applications. In V. Zimmer (Eds.), Gene Delivery: Methods and Applications (pp. 1-75). Nova Science Publishers. ISBN 9781536162684.

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Cristiana Silva Ulpiano