Carlos Rodrigues

Carlos A.V. Rodrigues

assistant researcher

H-7714-2013

Web of Science profile

iBB Group: scerg

carlos.rodrigues@tecnico.ulisboa.pt

Expertise: Stem Cells, Bioreactors, Bioprocess Engineering, Cellular Agriculture, Cultivated Seafood

Short Bio:

Carlos Rodrigues holds a MSc in Biological Engineering (IST) and a PhD in Bioengineering (IST). Currently, Carlos Rodrigues is an assistant researcher at the iBB - Institute for Bioengineering and Biosciences / i4HB - Institute for Health and Bioeconomy where he coordinates the "Bioreactor and Biomaterial Technologies for Stem Cell Manufacturing Lab". He is also invited assistant professor at the Department of Bioengineering of Instituto Superior Técnico. His research has focused on the development of bioreactor systems for the scalable cultivation of pluripotent stem cells, combining experimental and computational tools such as machine learning or computational fluid dynamics. Carlos Rodrigues is currently applying his experience in animal cell culture to the emerging area of cellular agriculture. He is co-founder of CellAgri Portugal, the Portuguese association for the development of Cellular Agriculture.

Research Focus:

Development of bioprocesses for the manufacturing of stem cells and their derivatives for biomedicine and cellular agriculture applications

SMART – New technologies for Stem cell Manufacturing bioprocess monitoring and ARTificial intelligence-based modeling (PTDC/EQU-EQU/3853/2020)
CARDIOWHEEL – Upscaling the Production of Human Pluripotent Stem Cell-derived Cardiomyocytes using Vertical-Wheel Bioreactors (PTDC/EQU-EQU/29653/2017)

VitaminSea – Enhancing Cost-Effective and Efficient Nutrient Delivery in Fish Embryonic Stem Cell Culture Medium via Functional Bioactive Microcarriers
(The Good Food Institute, 22-CM-PT-DG-1-317)

Europe Food Biofutures (EIT Food, 21362-24-A2401 | 12247)

Nogueira, D. E. S., Rodrigues, C. A. V., Carvalho, M. S., Miranda, C. C., Hashimura, Y., Jung, S., Lee, B., & Cabral, J. M. S. (2019). Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheel™ bioreactors. Journal of Biological Engineering, 13, 74. https://doi.org/10.1186/s13036-019-0204-1

Salvador, W. O. S., Nogueira, D. E. S., Ferreira, F. C., Cabral, J. M. S., & Rodrigues, C. A. V. (2023). BEMSCA: A novel decision support tool applied to the optimal design of a large-scale human induced pluripotent stem cell expansion bioprocess. Current Research in Biotechnology, 6, 100163. http://dx.doi.org/10.1016/j.crbiot.2023.100163

Agostinho, S. P., Branco, M. A., Nogueira, D. E. S., Diogo, M. M., Cabral, J. M. S., Fred, A. L. N., & Rodrigues, C. A. V. (2024). Unsupervised analysis of whole transcriptome data from human pluripotent stem cells cardiac differentiation. Scientific Reports, 14, 3110. http://dx.doi.org/10.1038/s41598-024-52970-z

Neto, P. M., Nogueira, D. E. S., Hashimura, Y., Jung, S., Pedras, B., Berberan-Santos, M. N., Palmeira, T., Lee, B., Cabral, J. M. S., Geraldes, V., & Rodrigues, C. A. V. (2022). Characterization of the aeration and hydrodynamics in Vertical-Wheel™ bioreactors. Bioengineering, 9(8), 386. https://doi.org/10.3390/bioengineering9080386

Salvador, W. O. S., Ribeiro, I. A. B., Nogueira, D. E. S., Ferreira, F. C., Cabral, J. M. S., & Rodrigues, C. A. V. (2022). Bioprocess economic modeling: Decision support tools for the development of stem cell therapy products. Bioengineering, 9(12), 791. https://doi.org/10.3390/bioengineering9120791

iBB People

Carlos A.V. Rodrigues