Arsenio M. Fialho
Cell penetrating p28 peptide-mediated delivery of nanomedicines for cancer treatment. Contract: PTDC/BTM-SAL/30034/2017
Virulence-associated Trimeric Autotransporter Adhesins from Burkholderia cenocepacia: functional, biophysical and structural characterization. Contract: PTDC/BIA-MIC/118386/2010
Bacterial protein azurin as a new candidate drug to treat untreatable breast cancers. Contract: PTDC/EBB-BIO/100326/2008
R Estevens, D Mil-Homens, AM Fialho (2023). In-Silico Analysis Highlights the Existence in Members of Burkholderia cepacia Complex of a New Class of Adhesins Possessing Collagen-like Domains. Microorganisms 11 (5), 1118
https://doi.org/10.3390/microorganisms11051118
Garizo AR, Coelho LF, Pinto S, Dias TP, Fernandes F, Bernardes N, Fialho AM (2021). The Azurin-Derived Peptide CT-p19LC Exhibits Membrane-Active Properties and Induces Cancer Cell Death. Biomedicines,10;9(9):1194
https://doi.org/10.3390/biomedicines9091194
Garizo AR, Castro F, Martins C, Almeida A, Dias TP, Fernardes F, Barrias CC, Bernardes N, Fialho AM*, Sarmento B* (2021) p28-functionalized PLGA nanoparticles loaded with gefitinib reduce tumor burden and metastases formation on lung cancer. Journal of Controlled Release, 337:329-342
https://doi.org/10.1016/j.jconrel.2021.07.035
Pimenta AI, Kilcoyne M, Bernardes N, Mil-Homens D, Joshi L, Fialho AM (2021) Burkholderia cenocepacia BCAM2418-induced antibody inhibits bacterial adhesion, confers protection to infection and enables identification of host glycans as adhesin targets” Cellular Microbiology, e13340,
doi: 10.1111/cmi.13340
Pimenta AI, Bernardes N, Alves MM, Mil-Homens D, Fialho AM (2021) Burkholderia cenocepacia transcriptome during the early contacts with giant plasma membrane vesicles derived from live bronchial epithelial cells. Scientific Reports
doi.org/10.1038/s41598-021-85222-5, 2021