Expertise: Extracellular Vesicles; Human Mesenchymal Stromal Cells; Immunomodulatory Potential; Process development; Economic Evaluation
Short Bio:
Ana Lúcia Tiago is a PhD Student in Bioengineering, working on the optimization of the GMP-compliant manufacturing of mesenchymal stromal cells-derived extracellular vesicles. After finishing her Integrated Masters in Biomedical Engineering (2020), having successfully completed her master thesis at SCERG-iBB, Ana Lúcia worked in consulting for the pharmaceutical industry for 2 years, having returned to SCERG in 2023 for her PhD. She is interested in establishing new functional assays for MSCs and their EVs, focusing on their immunomodulatory and hematopoietic support potential, to eventually aid the development of effective cell-free therapies for autoimmune diseases.
Research Focus:
Optimization of the GMP-compliant manufacturing of mesenchymal stromal cells-derived extracellular vesicles with immunomodulatory potential for advanced cell-free therapies
Branco A, Tiago AL, Laranjeira P, Carreira MC, Milhano JC, Dos Santos F, Cabral JMS, Paiva A, da Silva CL, Fernandes-Platzgummer A. Hypothermic Preservation of Adipose-Derived Mesenchymal Stromal Cells as a Viable Solution for the Storage and Distribution of Cell Therapy Products. Bioengineering (Basel). 2022 Dec 14;9(12):805. doi: 10.3390/bioengineering9120805. PMID: 36551011; PMCID: PMC9774331.