Prodigiosin has an enormous potential regarding its applicability as a natural pigment and pharmaceutical agent, but its commercialization remains scarce. The major limitations are related to the lack of efficient bioprocesses and scaling up from laboratory to production.
In a recently published paper, Ricardo Pereira and Carla C.C.R. de Carvalho improved prodigiosin yields during scale-up by mimicking the aeration conditions found at the sampling site.
When the inoculum was grown for 5 h at 200 rpm and for 19 h at 25 rpm, which significantly decreased the oxygen available, the cells produced 588.2 mg product/g biomass, corresponding to a production of 1066.2 mg of prodigiosin in 24 h and a productivity of 36.1 mg product/(L.h).
Link to publication: https://lnkd.in/d8bz9EMk