Selected Projects
2016
NanoMicroImpact - Impact of engineered nanoparticles and
microplastics on textile wastewater treatment with aerobic granular sludge
technology
Ref: PTDC/AAG-TEC/4501/2014
Principal Investigator: Nídia D. Lourenço
Start date: 01/05/2016
Duration: 36 months
YEASTPEC - Engineering of the yeast Saccharomyces cerevisiae for bioconversion of pectin-containing agro-industrial side-streams
ERA-NET Industrial Biotechnology
Principal Investigator of the IST team: Isabel Sá-Correia
Contract: ERA-IB-16-013
Starting date: January 1 2017
Duration: 36 months
TTRAFFIC – Toxicity and Transport for Fungal Production of Industrial Compounds
ERA-NET Industrial Biotechnology
Principal Investigator of the IST team: Nuno Mira
Contract: ERA-IB-2-6/0003/2014
Starting date: April 1 2016
Duration: 36 months
CNCVir - The coding and noncoding virulome of Burkholderia cenocepacia
Principal investigator: Jorge Humberto Leitão
Contract: PTDC/MAR-BIO/1547/2014
Starting date: April 1 2016
Duration: 36 months
Harnessing the power of the microbial metamobilome: using marine sponges as models to uncover novel biotechnological appliances from symbiont communities
Principal investigator: Rodrigo da Silva Costa
Contract: PTDC/MAR-BIO/1547/2014
Starting date: July 1 2016
Duration: 36 months
Structural and functional analysis of the Haa1 transcription factor required for yeast response and resistance to acetic acid
Principal investigator at IST: Isabel Sá-Correia
Contract: PTDC/BBB-BEP/0385/2014
Starting date: May 1 2016
Duration: 36 months
Molecular and Mechanical Forces in Biology measured with Force Feedback Microscopy
Principal investigator at IST: Isabel Sá-Correia
Contract: PTDC/FIS-NAN/6101/2014
Starting date: May 1 2016
Duration: 36 months
CANTROL - Deciphering the mechanisms of transcriptional regulation that control antifungal drug resistance in the pathogenic yeast Candida glabrata: aiming the development of improved diagnosis and therapeutic approaches
Principal investigator: Miguel Cacho Teixeira
Contract: PTDC/BBB-BIO/4004/2014
Starting date: March 1 2016
Duration: 36 months
SMARTWINE – Smarter wine fermentations: integrating Omic-tools for the development of novel mixed-starter cultures for tailored-made wine production
Principal investigator at IST: Nuno P Mira
Contract: PTDC/AGR-TEC/3315/2014
Starting date: May 1 2016
Duration: 36 months
Bioengineering the Neural Commitment of Human Pluripotent Stem Cells: Rational Approaches for the Clinical-Grade Production of Neuronal Cells
Ref: EXPL/BBB-EBI/0294/2013
Principal investigator: Tiago Fernandes
Starting Date: January 1 2014
Duration: 12 months
CARDIOSAFER –Safety and efficacy of intracoronary mesenchymal stem/stromal cell (MSC)-based therapy for myocardial regeneration: a microcirculation study
Ref: EXPL/BIM-MED/1970/2013
Principal Investigator: Cláudia Lobato da Silva
Starting Date: 1 Jan 2014
Duration: 12 months
LEVITA-Towards microbial sustainable production of itaconic and levulinic acids Ref: EraSynBio Twinning program
Principal Investigator: Nuno P Mira (Partners from Portugal, Austria, The Netherlands and United States of America)
Starting date: April 1 2014
Duration: 6 months
MFS-stress-Major Facilitator Superfamily transporters in the context of modern agriculture constraints: exploratory studies
Ref: EXPL/AGR-PRO/1013/2013
Principal investigator: Isabel Sá-Correia
Starting Date: January 1 2014
Duration: 12 months
PANCANDIDA – Towards the development of novel diagnosis tools for the early detection of invasive infections caused by C. albicans and C. glabrata
Ref: Gilead Génese Program.
Principal Investigator: Nuno P Mira;
Starting date: 1 Jan 2014;
Duration: 24 months
PhysBioFFM - Biological physics studies based on Force Feedback Microscopy
Ref: EXPL/FIS-NAN/1395/2013
Principal Investigator: ISabel Sá-Correia;
Starting date: 21 February 2014;
Duration: 12 months
Bioreg Rede SUDOE de Medicina Regenerativa/ BIOREG: SUDOE Regenerative Medicine Network
Ref:SOE3/P1/E750
Starting date 1 Jan 2013
Duration:24 months
DEMOCON - Decentralized wastewater treatment monitoring and control
Ref: PTDC/AAG-TEC/4124/2012
Principal Investigator: Helena M. Pinheiro
Start date: 15/05/2013
Duration: 24 months
EFICARE, Modelo de Monitorização do Desempenho da Gestão da Manutenção, Eficiência Energética e Qualidade do AR Interior (QREN)
Ref: 08/SI/2012
Participant: Teresa Pinheiro (IST)
Starting date: 2013
Duration: 24 months
GenoSep: Removal of Genotoxic impurities from active pharmaceutical ingredients
Ref: PTDC/QEQ-PRS/2757/2012,
Project leader: Frederico Castelo Ferreira
Starting date: July 2013
Duration: 24 months
Immunomics-Bcc: Exploitation of immunogenic proteins of the Burkholderia cepacia complex to design new diagnostic and therapeutic strategies
Ref: PTDC/BBB-BIO/1958/2012
Principal Investigator: Sílvia Sousa
Starting date: April 2013
Duration: 24 months
BIOTEXTILE - Sequencing batch reactor biotechnology toward effective textile wastewater treatment
Ref: PTDC/EBB-EBI/120624/2010
Principal Investigator: Nídia D. Lourenço
Start date: 01/02/2012
Duration: 36 months
FUNDRING: Identification of new biomarkers for antifungal drug resistance diagnosis in Candida glabrata: the particular role of multidrug resistance transporters
Ref: PTDC/EBB-BIO/119356/2010
Principal investigator: Miguel Cacho Teixeira
Start date: 01/01/2012
Duration: 36 months
INTENSO - Gaining productivity, Cost Efficiency and Sustainability in the Downstraming Processing of Bio Products by novel Integration and Intensification Strategies
Ref.: European Project
Principal Investigator IST: Maria Raquel Múrias Santos Aires Barros
Start Date: 01-08-2012
Duration: 54 months
ROOT-INT - Role of a two-component regulatory system in the early interaction between Sinorhizobium meliloti and plant root hairs
Ref: PTDC/BIA-MIC/111733/2009
Principal investigator: Leonilde M Moreira
Start date: 01/01/2011
Duration: 36 months
Bacterial protein azurin as a new candidate drug to treat untreatable breast cancers
Ref: PTDC/EBB-BIO/100326/2009
Principal investigator: Arsénio M Fialho
Start date: 01/01/2011
Duration: 36 months
INTACT - Integral engineering of acetic acid tolerance in yeast
ERA-NET Industrial Biotechnology
REf: ERA-IB/0002/2010
Principal Investigator of the IST team: Isabel Sá-Correia
Start date: March 2011
Duration: 41 months
Microbial cell surface determinants of virulence as targets for new therapeutics in Cystic fibrosis
Ref: COST Action BM1003
Principal Investigator of the IST team: Isabel Sá-Correia
Start date: March 2011
Duration: 48 months
Study of NPs interaction with cells, using methodologies based on IBA (Ion Beam Analysis) techniques.
Ref: Governo de Espanha, Ministerio para a Ciência e Innovación
Participants: Teresa Pinheiro (IST)
Starting date: 2011
Duration: 36 months
TerbAzineBiorem - Studies on the efficacy and scale-up of bioremediation strategies for soils contaminated with the herbicide terbuthylazine
Ref: PTDC/AAC-AMB/111317/2009
Principal investigator: Cristina Anjinho Viegas
Start date: 01/01/2011
Duration: 36 months
New tailor-made PHB-based nanocomposites for high performance applications produced from environmentally friendly production routes
Principal Investigator of the IST team: M. Manuela da Fonseca
Contract: EU 246449
Start date: 01/07/2010
Duration: 48 months
Membrane chromatographic matrices for plasmid-DNA purification: rational design based on biochemical and biophysical interactions
Ref.: PTDC/EBB-EBI/100925/2008
Principal Investigator IST: Marília Clemente Velez Mateus
Start Date: February 2010
Duration: 36 months
A Lab-on-a-chip-based 2D fluorescence detection system for organism/cell condition analysis (Micro-2D-FS)
Ref.: PTDC/CTM/104387/2008
Principal Investigator IST: Duarte Miguel de França Teixeira dos Prazeres
Start Date: January 2010
Duration: 36 months
Exploring human embryonic stem cell fate using 3-D cellular microarrays
Ref.: PTDC/EBB-BIO/101088/2008
Principal Investigator IST: Maria Margarida Fonseca Rodrigues Diogo
Start Date: January 2010
Duration: 36 months
Immunotherapy of African trypanosomiasis in the mouse model by DNA vaccination
Ref.: PTDC/CVT/102486/2008
Principal Investigator IST: Duarte Miguel de França Teixeira dos Prazeres
Start Date: January 2010
Duration: 36 months
Integrated Process for the Expansion and Neural Differentiation of Human Embryonic Stem Cells in Stirred Suspension Bioreactors
Ref.: PTDC/EQU-ERQ/105277/2008
Principal Investigator IST: Joaquim Manuel Sampaio Cabral
Start Date: January 2010
Duration: 36 months
Investigação, Conservação e Divulgação da Biodiversidade dos Charcos Temporários
Fundação EDP
Principal Investigator: Carla da Conceição Caramujo de Carvalho
Start Date: January 2010
Duration: 24 months
Development of microreactors for use in biocatalysis and bioproducts separation
Cooperação Cientifica e Tecnológica FCT/Eslovénia
Start Date: January 2010
Duration: 24 months
StemCellQCM - Acoustic detectors for stem cell adhesion and differentiation
Ref.: PTDC/SAU-BEB/105189/2008
Principal Investigator IST: Joaquim Manuel Sampaio Cabral
Start Date: April 2010
Duration: 36 months
Helper compounds against multidrug resistant bacteria: revealing their mechanism of action
Ref.: PTDC/BIA-MIC/105509/2008
Principal Investigator IST: Carla da Conceição Caramujo de Carvalho
Start Date: March 2010
Duration: 36 months
DSPmAb - Intensification of the downstream process of monoclonal antibodies
Ref.: PTDC/EQU-EPR/117427/2010
Principal Investigator IST: Ana Margarida Nunes da Mata Pires de Azevedo
Duration: 36 months
Defects Detection in Microfabrication With Bacterial Cells (MicroBac)
Ref.: PTDC/EME-TME/118678/2010
Principal Investigator IST: Carla da Conceição Caramujo de Carvalho
Duration: 36 months
Exploiting the type II phosphomannose isomerase BseAJ as a new target for the development of new antimicrobials and biotechnological applications
Ref: PTDC/EBB-BIO/098352/2008
Principal investigator: Jorge H Leitão
Start date: 01/01/2010
Duration: 36 months
ZygoSacAR - Mechanistic insights into acetic acid resistance in food spoilage yeasts: from the experimental model Saccharomyces cerevisiae to Zygosaccharomyces species
Ref: PTDC/AGR-ALI/102608/2008
Principal Investigator: Isabel Sá-Correia
Start date: 01/04/2010
Duration: 36 months
QCMTF - Biosensor platform for transcription factor DNA binding activity detection
Ref: PTDC/ EBB-EBI/108517 /2008
Principal Investigator at IST: Isabel Sá-Correia
Start date: 01/04/2010
Duration: 36 months
Resistance to pesticides and other chemical stresses of agricultural interest: role of plant Major Facilitator Superfamily transporters
Ref: PTDC/AGR-AAM/102967/2008
Principal Investigator at IST: Isabel Sá-Correia
Start date: 01/04/2010
Duration: 36 months
lRedox- Biomaterials: Design of new redox biomaterials and their application in Biofuel cells for the production of electrical energy, feedstock chemicals and building blocks
Ref.: PTDC/EBB-EBI/099237/2008
Principal Investigator IST: Luis Joaquim Pina da Fonseca
Start Date: September 2010
Duration: 36 months
PMfugitive: Mitigating the Environmental and Health Impacts of Particles from Fugitive Emissions.
Participants: Teresa Pinheiro (IST)
Ref: PTDC/AAC-AMB/098825/2008
Starting Date: 2010
Duration: 36 months
Innovative strategies for the purification of biopharmaceuticals: Magnetic Nanoparticles applied to High-Gradient-Magnetic-Separation and Aqueous-Two-Phase-Systems
Principal Investigator IST: Maria Raquel Múrias dos Santos Aires-Barros
Ref.: PTDC/EBB-BIO/098961/2008
Duration: 36 months
Integrated evaluation of nanomaterials: Characterization and Assessment of Environmental Toxicity – NanoTox.
Participant: Teresa Pinheiro (IST).
Ref: PTDC/CTM/099446/2008
Starting date: 2009
Duration: 36 Months
STEMSELECT - Novel integrated process for human hematopoietic stem cell isolation and ex-vivo expansion
Principal Investigator IST: Maria Raquel Múrias dos Santos Aires-Barros
Ref.: PTDC/EQU-EPR/104663/2008
Duration: 36 months
SYNBIOBACTHER - Synthetic biology approaches to engineer "therapeutic" bacteria
Principal Investigator IST: Gabriel Antonio Amaro Monteiro
Ref.: PTDC/EBB-BIO/102863/2008
Drug Release: Development of novel gelatine-based drug delivery systems using supercritical fluid technology
Principal Investigator IST: Nuno Miguel Torres Lourenço
Ref.: PTDC/EQU-EQU/104552/2008
Duration: 36 months
The relationship of circulating biomarkers of apoptosis and endothelial function with the plaque composition using VH IVUS.
Co-ordination: Teresa Pinheiro (IST)
Ref: FCT/PIC/IC/82734/2007
Starting date: 2009
Duration: 48 months
Thin Film Battery: Development of Ion jelly thin film printable batteries for smart devices
Principal Investigator IST: Nuno Miguel Torres Lourenço
Ref.: PTDC/CTM/100244/2008
Duration: 36 months
Smart small-scale devices: systems for controlled delivery of bioactive molecules, cell expansion and for sensing cell environment
MIT-Portugal
Principal Investigator: Cláudia Alexandra Martins Lobato da Silva
Ref.: MIT-Pt/BS-CTRM/0051/2008
Start Date: April 2009
Duration: 48 months
Sol-gel entrapped cutinase: Understanding enzyme/matrix interactions via fluorescence, NMR and DRIFT spectroscopies, and site-directed mutagenesis
Principal Investigator IST: Luis Joaquim Pina da Fonseca
Ref.: PTDC/QUI/64744/2006
Start Date: January 2009
Duration: 36 months
Scalable Reactor Systems for the Production of Human Mesenchymal Stem Cells
Principal Investigator IST: Cláudia Alexandra Martins Lobato da Silva
Ref.: PTDC/EQU-EQU/114231/2009
IonJelly Biosensors: Ion Jelly® technology as matrix for new biosensors
Principal Investigator IST: Luis Joaquim Pina da Fonseca
Ref.: PTDC/EBB-BIO/114288/2009
Improvement of the immunogenicity of DNA vaccines
Principal Investigator IST: Gabriel Antonio Amaro Monteiro
Ref.: PTDC/EBB-EBI113650/2009
Protein-Aqueous Environment Interactions
Principal Investigator IST: Maria Raquel Múrias Santos Aires Barros
Ref.: PTDC/EQU-EQU/112812/2009
ADHRES - Signature Project: Expression profiling of adhesive (ADH) and resistance (RES) genes in biofilm lifestyle in P. aeruginosa, P. putida and B. cenocepacia
ERA-NET PathoGenomics
Principal Investigator of the IST team: Isabel Sá-Correia
Contract: ERA-PTG/SAU/0001/2008
Start date: February 2009
Duration: 36 months
Insights into the mechanisms underlying the acquisition of antimicrobial resistance during chronic lung infection and the pathogenicity of Burkholderia cenocepacia
Funded by Cystic Fibrosis Foundation Therapeutics, a nonprofit affiliate to the Cystic Fibrosis Foundation - Burkholderia array project BA-009-A
Principal Investigator of the IST team: Isabel Sá-Correia
Start date: September 2008
Duration: 6 months
Imatinib Resistance and Targets in Chronic Myeloid Leukaemia: Post-Genomic Approaches using Yeast as Model System
Principal Investigator: Isabel Sá-Correia
Contract: PTDC/SAU-FCF/71760/2006
Start date: 01/01/2008
Duration: 36 months
Characterization and modeling of a specific transcriptional regulatory network required for multidrug resistance in yeast.
Principal Investigator: Isabel Sá-Correia
Contract: PTDC/BIO/72063/2006
Start date: 01/01/2008
Duration: 36 months
Functional and biochemical analysis of the yeast multidrug resistance transporters Qdr2 and Aqr1
Principal Investigator: Miguel Cacho Teixeira
Contract: PTDC/BIA-MIC/72577/2006
Start date: 01/06/2008
Duration: 36 months
ARN - Algorithms for the identification of Genetic Regulatory Networks
Principal Investigator of the IST team: Isabel Sá-Correia
Contract: PTDC/EIA/67722/2006
Start date: 01.01.2008
Duration: 36 months
Dyablo: models for the dynamic behaviour of Biological Networks
Principal Investigator of the IST team: Isabel Sá-Correia
Contract: PTDC/EIA/71587/2006
Start date: 01.01.2008
Duration: 36 months
Optimization and control of intermittent UASB reactors and microbial population dynamics
Principal Investigator of the IST team: Jorge Humberto Leitão
Contract: PTDC/AMB/65025/2006
Start date: 01/01/2008
Duration: 36 months
Please click on here to see national and international projects coordinated by members from BERG and/or BSRG since 1994 until 2007.