Joana C. Ricardo
PhD Student



Research Activities

I have been involved in several projects that aimed to study different peptides / proteins, namely lysozyme, GAPDH, insulin, calcitonin and islet amyloid polypeptide (IAPP), in the context of amyloid and amyloid-like fibril formation using a variety of biophysical techniques. We employed essentially steady-state and time-resolved fluorescence methodologies, including anisotropy, FLIM, FAIM, FCS and FRET, to study peptide-peptide and peptide-lipid interactions and characterize the resulting structures.

Selected Publications

Melo A, Ricardo JC, Federov A, Prieto M, Coutinho A. (2013) Fluorescence Detection of Lipid-Induced Oligomeric Intermediates Involved in Lysozyme “Amyloid-like” Fiber Formation Driven by Anionic Membranes. J Phys Chem B. 117(10): 2906-17 doi: 10.1021/jp310396v

 

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ORCID