Eduardo Brás
PhD Student
Research Activities
My research is being developed from a collaboration between IBB and
INESC Microsystems and Nanotechnologies, under the Advanced Integrated
Microsystems doctoral program. My work is supervised by Professor João
Pedro Conde and Professor Pedro Fernandes and focuses on the
application of enzymatic reactions in tailored made microfluidic chips.
Two potential applications will be studied: (i) biosensing of
metabolites (in plants, animals and humans); (ii) screening of
production conditions for high value added biotechnological products.
In addition, the integration of additional processing modules to the
microfluidic microreactor will be studied: (i) sample preparation; (ii)
downstream separation. In the past I've worked on the development of
microfluidic reactors for the cultivation of yeast cells and on the
development of a microfluidic approach to optimise the purification of
biomolecules through the use of aqueous two-phase systems.
Selected Publications
Bras, E.J.S., Chu, V., Aires-Barros, M.R., Conde, J.P., Fernandes, P., “A microfluidic platform for physical entrapment of yeast cells with continuous production of invertase”, J. Chem. Technol. Biotechnol. 92 (2017) 334-341. doi: 10.1002/jctb.5010
Development of a Point-of-Care Platform for Plant Health Assesment: A Microfluidic Approach, Oral Presentation at the 32nd Edition of the Eurosensors Conference, 2018;
Rapid and multiplexed screening of aqueous two-phase systems for the affinity driven partition of biopharmaceuticals using a microfluidic toolbox, Oral Presentation at Anything But Conventional Chromatography, ESBES Workshop 2017;
Best poster award at the Microbiotec'17 conference in Porto for the work: "Affinity driven aqueous-two phase extraction of antibodies: a microfluidic approach."
E-mail (click on)