Articles in peer-review journals - 2013



Aguiar-Oliveira, E., Fernandes, P., Cabral, J. M. S., Maugeri, F., "Characterisation of biocatalysts immobilised in niobium—a new inorganic solid support", Canadian J. Chem. Eng., 91, 432–440 (2013)


Almeida, S.M., Freitas, M.C., Reis, M., Pinheiro, T., Felix, P.M., Pio, C.A., “Fifteen Years of Nuclear Techniques Application to Suspended Particulate Matter Studies”, The Journal of Radioanalytical and Nuclear Chemistry, 297(3), 347-356 (2013)


Andrade, P.Z., de Soure, A.M., dos Santos, F., Paiva, A., Cabral J.M.S., da Silva, C.L., “Ex vivo expansion of cord blood haematopoietic stem/progenitor cells under physiological oxygen tensions: clear-cut effects on cell proliferation, differentiation and metabolism”, J. Tissue Eng. Regen. Med. doi: 10.1002/term.1731. (2013)


Andrade, P.Z., dos Santos, F., Cabral, J.M.S., da Silva, C.L., “Stem cell bioengineering strategies to widen the therapeutic applications of haematopoietic stem/progenitor cells from umbilical cord blood”, J. Tissue Eng. Regen. Med. doi: 10.1002/term.1741. (2013)


Barbas, A., Popescu, A., Frazão, C., Arraiano, C.M., Fialho, A.M., "Rossmann-fold motifs can confer multiple functions to metabolic enzymes: RNA binding and ribonuclease activity of a UDP-glucose dehydrogenase", Biochemical & Biophysical Research Communications, 430(1):218-24 (2013)


Barreiros, M.A., Pinheiro, T., Felix, P.M., Franco, C., Santos, M., Araújo, F., Freitas, M.C., Almeida, S.M., “Exhaled Breath Condensate as a biomonitor for metal exposure: A new analytical challenge”, J. Radional Nucl Chem”, 297, 377-382 (2013)


Bernardes N., Ribeiro A.S., Abreu S., Mota B., Matos R.G., Arraiano C.M., Seruca R., Paredes J., Fialho A.M. “The bacterial protein azurin impairs invasion and FAK/Src signaling in P-cadherin-overexpressing breast cancer cell models” PLoS One, 8 (7), e69023 (2013)


Bernardes, N., Chakrabarty, A.M., Fialho, A.M., "Engineering of bacterial strains and their products for cancer therapy", Applied Microbiology and Biotechnology, 97(12):5189-99 (2013)


Borlido, L.B., Azevedo, A.M., Roque, A.C.A., Aires-Barros, M.R., "Magnetic separations in biotechnology", Biotechnol. Adv., ( j.biotechadv.2013.05.009) (2013)


Borlido, L.B., Moura, L., Azevedo, A.M., Roque, A.C.A., Aires-Barros, M.R., Farinha, J.P.S., "Stimuli-Responsive Magnetic Nanoparticles for Monoclonal Antibody Purification", Biotechnol. J., 8, 709-717 (2013)


Boura, J.S., dos Santos, F., Gimble, J.M., Cardoso, C.M., Madeira, C., Cabral, J.M., da Silva, C.L., “Direct head-to-head comparison of cationic liposome-mediated gene delivery to mesenchymal stem/stromal cells of different human sources: a comprehensive study”, Hum Gene Ther Methods, 24(1), 38-48 (2013)


Brito, R.S., Ferreira, F. Lourenço, N.D., Pinheiro, H.M. and Matos, J.S., “Espectrofotometria para monitorização da qualidade de água residual em drenagem urbana”, Revista Recursos Hídricos, 34(1), 5-16 (2013)


Campenni', L., Nobre, B.P., Santos, C.A., Oliveira, A.C., Aires-Barros, M.R., Palavra, A.M.F., Gouveia, L., “Carotenoid and lipid production by the autotrophic microalga Chlorella protothecoides under nutritional, salinity, and luminosity stress conditions”, Appl. Microbiol. Biotechnol., 97(3), 1383-1393 (2013)


Carvalho, F., Paradiso, P., Fernandes, P., "A microscopic perspective of a microreactor", Microsc. Microanal. 19, Suppl. 4, 33-34 (2013)


Cavalheiro, J. M. B. T., E. Pollet, H.P. Diogo, M.T. Cesário, L. Avérous, M.C.D . de Almeida, M.M.R da Fonseca (2013), “On the heterogeneous composition of bacterial polyhydroxyalkanoate terpolymers”, Bioresour Technol 147, 434–41.


Cesário, T., R.S. Raposo, M.C.D. de Almeida, F. van Keulen, B.S. Ferreira, M.M.R da Fonseca (2013) “Enhanced bioproduction of poly-3-hydroxybutyrate from wheat straw lignocellulosic hydrolysates”, New Biotechnol 31, 104-113


Contesini, F.J., Figueira, J.A., Kawaguti, H.Y., Fernandes, P.C.B., Carvalho, P.O., Nascimento, M.G., Sato, H.H., "Potential Applications of Carbohydrases Immobilization in the Food Industry", Int. J. Mol. Sci., 14, 1335-1369 (2013)


Costa, C., Henriques, A.S., Pires, C., Nunes, J., Ohno, M., Chibana, H., Sá-Correia, I., Teixeira, M.C., "The dual role of Candida glabrata Drug:H+ Antiporter CgAqr1 (ORF CAGL0J09944g) in antifungal drug and acetic acid resistance", Frontiers in Microbiology, 4:170 (2013)


Costa, C., Pires, C., Cabrito, T.R., Renaudin, A., Ohno, M., Chibana, H., Sá-Correia, I., Teixeira, M.C., "Candida glabrata drug:H+ antiporter CgQdr2 (ORF CAGL0G08624g) confers imidazole drug resistance, being activated by the CgPdr1 transcription factor", Antimicrobial Agents and Chemotherapy, 57(7):3159-67 (2013)


Costa, C., Pires, C., Cabrito, T.R., Renaudin, A., Ohno, M., Chibana, H., Sá-Correia, I., Teixeira, M.C., "Candida glabrata drug:H+ antiporter CgQdr2 (ORF CAGL0G08624g) confers imidazole drug resistance, being activated by the CgPdr1 transcription factor", Antimicrobial Agents and Chemotherapy, 57(7), 3159-67 (2013)


de Carvalho, R. N. L.; Torres Lourenço, N. M.; Gomes, P. M. V.; da Fonseca, L. J. P., “Swelling behavior of gelatin-ionic liquid functional polymers”. Journal of Polymer Science Part B: Polymer Physics, 51 (10), 817-825 (2013).


de La Vega, J., Ter Braak, B., Azzoni, A.R., Monteiro, G.A., Prazeres, D.M. F., “Impact of Plasmid Quality on Lipoplex-Mediated Transfection”, J. Pharm. Sci., 102(11), 3932-3941 (2013)


de Lima, A.P. D., Eugen M. Aschenbrenner, Sâmeque do N. Oliveira, Jean-Baptiste Doucet, Clemens K. Weiss∗, Ulrich Ziener, Luís P. Fonseca, Nágila M.P.S. Ricardo, Liane L. de Freitas, Cesar L. Petzhold, Katharina Landfester “Towards regioselective enzymatic hydrolysis and glycerolysis of tricaprylin in miniemulsion and the direct preparation of polyurethane from the hydrolysis products” Journal of Molecular Catalysis B: Enzymatic, 98 (2013) 127–137.


Dias, PJ, I Sa-Correia, “The drug:H+ antiporters of family 2 (DHA2), siderophore transporters (ARN) and glutathione:H+ antiporters (GEX) have a common evolutionary origin in hemiascomycete yeasts”, BMC Genomics, MS ID: 1864181948943529, 2013


Di Lorenzo F, Silipo A, Lanzetta R, Fazio LL, Paciello I, Coutinho CP, Sá-Correia I, Bernardini M, Molinaro A. Structural elucidation and biological activity of the lipooligosaccharide of a Burkholderia dolosa isolate from a cystic fibrosis patient. ChemBioChem, 14 (9):1105–1115 (2013)


Donato, S.S., Chu, V., Prazeres, D.M.F., Conde, J.P., “Metabolic viability of Escherichia coli trapped by dielectrophoresis in microfluidics”, Electrophoresis, 34(4), 575-582 (2013)


dos Santos, F.F., Andrade, P.Z., da Silva, C.L., Cabral, J.M., “Bioreactor design for clinical-grade expansion of stem cells”, Biotechnol J., 8(6), 644-54 (2013)


Dsouza, R.N., Azevedo, A.M., Aires-Barros, M.R., Krajnc, N.L., Kramberger, P., Carbajal, M.L., Grasselli, M., Meyer, R., Fernández-Lahore, M., “Emerging Technologies for the Integration and the Intensification of Bioprocesses”, Pharm. Bioprocess., in press (2013)


El-Kirat, S., Mil-Homens, D., Beaussart, A., Fialho, A.M., Dufrêne, Y.F., "Single-molecule atomic force microscopy unravels the binding mechanism of a Burkholderia cenocepacia trimeric autotransporter adhesin", Molecular Microbiology, doi: 10.1111/mmi.12301, (2013)


Eusébio, N., Coutinho, C., Sá-Correia, I., Araújo, R., "SNaPBcen: a novel and practical tool for genotyping Burkholderia cenocepacia", Journal of Clinical Microbiology, in press (2013)


Félix, P.M., Franco, C., Barreiros, M.A., Batista, B., Bernardes, S., Garcia, S.M., Almeida, A.B., Almeida, S.M., Wolterbeek, H.Th., Pinheiro, T., “Biomarkers of exposure to metal dust in exhaled breath condensate: methodology optimization”, Archives of Environmental and Occupational Health, 68(2), 72-79 (2013)


Félix, P.M., Almeida, S.M., Pinheiro, T., Sousa, J., Franco, C., Wolterbeek, H.Th., “Assessment of exposure to metals in lead processing industries”, Int. J. Environm. Health, 216, 17–24 (2013)


Fernandes, T.G., Rodrigues, C.A.V., Diogo, M.M., Cabral, J.M.S., “Stem cell bioprocessing for Regenerative Medicine”, J Chem Technol Biot, DOI: 10.1002/jctb.4189 (2013)


Ferreira, A.S., Silva, I.N., Oliveira, V.H., Becker, J.D., Givskov, M., Ryan, R.P., Fernandes, F., Moreira, L.M., "Comparative transcriptomic analysis of the Burkholderia cepacia tyrosine kinase bceF mutant reveals a role in tolerance to stress, biofilm formation and virulence", Applied and Environmental Microbiology, 79(9):3009-20, (2013)


Figueira, J.A., Sato, H.H., Fernandes, P., "Establishing the feasibility of using β-glucosidase entrapped in Lentikats® and in sol-gel supports for cellobiose hydrolysis", J. Agric. Food Chem., 61, 626-634 (2013)


Godinho, R.M., Raimundo, J., Vale, C., Anes, B., Brito, P., Alves, L.C., Pinheiro, T., “Micro-scale elemental partition in tissues of the aquatic plant Lemna minor L. exposed to highway drainage water”, Nucl. Instrum. Methods B, 306, 150-152 (2013)


Gonçalves, G.A.L., Prazeres, D.M.F., Monteiro, G.A., Prather, K.L.J., "De novo creation of MG1655-derived E. coli strains specifically designed for plasmid DNA production", Appl. Microbiol. Biot., 97, 611-620 (2013)


Hakemeyer C, Strauss U, Werz S, Folque F, Menezes JC . Assessment of Raw Materials Variability and their impact on Mab Fermentations: a study with aged media components. J. Biotechnol. (Wiley) – in press (DOI: 10.1002/biot.201200355) (2013)


Lourenço, A.B., Roque, F.C., Teixeira, M.C., Ascenso, J.R., Sá-Correia, I., "Quantitative 1H-NMR-metabolomics reveals extensive metabolic reprogramming and the effect of the aquaglyceroporin FPS1 in ethanol stressed yeast cells", PLoS One, 8 (2): e55439, (2013)


Madeira, C., Rodrigues, C.A.V., Reis, M.S.C., Ferreira, F.C.G., Correia, R.E.S.M., Diogo MM, Cabral JMS, "Non-viral gene delivery to neural stem cells with minicircles by microporation", Biomacromolecules, 14(5):1379-1387 (2013)


Madeira, P.P., Bessa, A., Alvares-Ribeiro, L., Aires-Barros, M.R., Rodrigues, A.E., Zaslavsky, B.Y., “Analysis of amino acid-water interactions by partitioning in aqueous two-phase systems. I-Amino acids with non-polar side-chains”, J. Chromatogr. A, 1274, 82-86 (2013)


Madeira, P. P., Bessa, A., de Barros, D.P.C, Teixeira, M. A.,Álvares-Ribeiro, L., Aires-Barros, M. R., Rodrigues, A. E.,Chait, A., Zaslavsky, B. Y. ”Solvatochromic relationship: Prediction ofdistribution of ionic solutes in aqueous two-phase systems”, Journal of Chromatography A, 1271, 10 (2013)


Madeira, P.P., Bessa, A., Teixeira, M.A., Alvares-Ribeiro, L., Aires-Barros, M.R., Rodrigues, A.E., Zaslavsky, B.Y., “Study of organic compounds-water interactions by partition in aqueous two-phase systems”, J. Chromatogr. A, 1332, 97-104 (2013)


Martins, D.C., Chu, V., Prazeres, D.M.F., Conde, J.P., “Streaming currents in microfluidics with integrated polarizable electrodes”, Microfluid. Nanofluid., 15(3), 361-376 (2013)


Martins, S.A.M., Moulas, G., Trabuco, J.R.C., Monteiro, G.A., Chu, V., Conde, J.P., Prazeres, D.M.F., "Monitoring intracellular calcium in response to GPCR activation using thin-film silicon photodiodes with integrated fluorescence filters", Biosens. Bioelectron. ,52, 232-238 (2013) doi:10.1016/j.bios.2013.08.037


Moreira, F., Badenes, S.M., Cabral, J.M.S., "Biocatalytic transesterification of triglycerides and alcohols for the production of biodiesel using cutinase in organic media", Biocatalysis and Biotransformation, 31, 246-254 (2013)


Novo, P., Moulas, G., Prazeres, D.M.F., Chu, V., Conde, J.P., “Detection of ochratoxin A in wine and beer by chemiluminescence-based ELISA in microfluidics with integrated photodiodes”, Sens. Actuators B, 176, 232-240 (2013)


Nunes, M.A.P., Fernandes, P.C.B., Ribeiro, M.H.L., "Microtiter plates versus stirred mini-bioreactors in biocatalysis: A scalable approach", Bioresource Technol., 136, 30-40 (2013)


Oliveira, P.H., Boura, J.S., Abecasis, M.M., Gimble, J.M., da Silva, C.L., Cabral, J.M.S., “Impact of hypoxia and long-term cultivation on the genomic stability and mitochondrial performance of ex-vivo expanded human stem/stromal cells”, Stem Cell Res., 9(3), 225-236 (2013)


Oliveira PH, da Silva CL, Cabral JM, “An appraisal of human mitochondrial DNA instability: new insights into the role of non-canonical DNA structures and sequence motifs”, PLoS One; 8(3), e59907 (2013)


Pinheiro,T., R. Silva, R. Fleming, A. Gonçalves, M.A. Barreiros, J. N. Silva, P. Morlière, R. Santus, P. Filipe. Primary hemochromatosis: Distribution and quantitation of skin iron. Correlations with total body stores. Acta Dermato-Venereologica. 2013; online (doi: 10.2340/00015555-1601)


T. Pinheiro, L. Moita, L. Silva, E. Mendonça, A. Picado. Nuclear microscopy as a tool in TiO2 nanoparticles bioaccumulation studies in aquatic species. Nucl Instrum Methods B 2013; 306:117-120 (2013)


Prazeres, D.M.F., "Histórias de Inovação Aberta", Ingenium, Jul/Ago, 68-71 (2013)


Raiado-Pereira, L., Prazeres, D.M.F., Mateus, M., “Impact of plasmid size on the purification of model plasmid DNA vaccines by phenyl membrane adsorbers”, J. Chromatogr. A, 1315, 145-151 (2013)


Ramos, C.G., Grilo, A.M., da Costa, P.J., Leitão, J.H. Experimental identification of small non-coding regulatory RNAs in the opportunistic human pathogen Burkholderia cenocepacia J2315. Genomics 101(2):139-148, (2013)


Raposeiro, I., Fonseca, M., Duarte, A.P., Bordado, J.M. “Functional Polyesters”, Macromol Symp. 331-332, 97-108. (2013) doi:10.1002/masy.201300071


Remy, E., Cabrito, T.R., Baster, P., Batista, R.A., Teixeira, M.C., Friml, J., Sá-Correia, I., Duque, P., "A Major Facilitator Superfamily Transporter Plays a Dual Role in Polar Auxin Transport and Drought Stress Tolerance in Arabidopsis", The Plant Cell, 25: 901-26, (2013)


Ribeiro, E.M., Fernandes, P., "Coated-wall mini reactor for inulin hydrolysis", Current Biotechnol., 2, 47-52 (2013)


Ribeiro, A., Laranjeira, P., Mendes, S., Velada, I., Leite, C., Andrade, P., Santos, F., Henriques, A., Grãos, M., Cardoso, C.M., Martinho, A., Pais, M., da Silva, C.L., Cabral, J., Trindade, H., Paiva, A., “Mesenchymal stem cells from umbilical cord matrix, adipose tissue and bone marrow exhibit different capability to suppress peripheral blood B, natural killer and T cells”, Stem Cell Res. Ther. 15-4(5),125 (2013)


Rosa, P.A.J., Azevedo, A.M., Sommerfeld, S., Bäcker, W., Aires-Barros, M. R., " Continuous purification of antibodies from cell culture supernatant: from concept to process", Biotechnol. J., 8, 352-362 (2013)


Salgado Brito, R., Pinheiro, H. M. , Ferreira, F., Saldanha Matos, J., Lourenço, N. D., "In situ UV-Vis spectroscopy to estimate COD and TSS in wastewater drainage systems", Urban Water Journal, (2013)


Santos, R.; Rocha, Â.; Matias, A.; Duarte, C.; Sá-Nogueira, I.; Lourenço, N.; Borges, J. P.; Vidinha, P., “Development of Antimicrobial Ion Jelly Fibers” RSC Advances, accepted, (2013)


Silva, C.S.O., Lansalot, M., Garcia, J.Q., Taipa, M.A., Martinho, J.G., “Synthesis and characterization of biomimetic nanogels for immunorecognition”, Colloids Surf. B, 112(12), 264-271 (2013)


Simões, I.N., Boura, J.S., dos Santos, F., Andrade, P.Z., Cardoso, C.M., Gimble, J.M., da Silva, C.L., Cabral, J.M., “Human mesenchymal stem cells from the umbilical cord matrix: successful isolation and ex-vivo expansion using serum-/xeno-free culture media”, Biotechnol J. doi: 10.1002/biot.201200340 (2013)


Simcikova, M., Prazeres, D.M.F., Monteiro, G.A., “Design, construção e produção de minicírculos como vectores de entrega de genes”, Boletim de Biotecnologia, 4, 28-30 (2013)


Sousa, I. T.; Lourenco, N. M. T.; Afonso, C. A. M.; Taipa, M. A., “Protein stabilization with a dipeptide-mimic triazine-scaffolded synthetic affinity ligand”. Journal of Molecular Recognition, 26 (2), 104-112 (2013)


Sousa, S.A., Feliciano, J.R., Pinheiro, P.F., Leitão J.H., "Biochemical and functional studies on the Burkholderia cepacia complex bceN gene, encoding a GDP-mannose 4,6-dehydratase", PLoS One. 2013;8(2):e56902 (2013)


Székely, G., Bandarra, J., Heggie W, Ferreira, F.C. “Environmental and economic analysis for selection and engineering sustainable API degenotoxification processes”, Green Chem. 15, 210 (2013)


Szekely, G., Gil, M., Sellergren, B., Heggie, W., Ferreira, F.C., “Environmental and economic analysis for selection and engineering sustainable API degenotoxification processes”, Green Chem., 15(1), 210-225 (2013)


Vicente J, Pinto J, Menezes JC, Gaspar F. Fundamental analysis of particle formation in spray drying. Powder Technol., 247, 1-7 (2013)


Articles in Conference Proceedings


Monteiro, B.J.C., Guerreiro, J.D.T., dos Santos, F., Cabral, J.S.M., da Silva, C.L., Ferreira, F.C., “Study of the Effec ts of Electrospun Poly(epsloncaprolactone)/Gelatin Matrices on Human Mesenchymal Stem Cell Culture”, IEEE 3rd Portuguese Bioengineering Meeting/ ENBENG 2013, Univ. Minho, Braga, February (WOS:000324857800042 – Paper) (2013)


Carvalho, F., Marques, M.P.C., Fernandes, P. “Continuous sucrose hydrolysis in microchannel reactors”, 2nd International Conference on Implementation of microreactor technology into biotechnology | IMTB 2013, Cavtat, Croatia, May (2013)


Pinheiro, T. and Ramos, C. and Napoleão, P. and Mendonça, C. and Fondinho, C. and Selas, M. and Mota Carmo, M. and Cruz Ferreira, R. Plaque vulnerability phenotype in patients with coronary artery disease: An intravascular ultrasound radiofrequency analysis: CARDIOTECHNIX 2013 - Proceedings of the International Congress on Cardiovascular Technologies 2013; pp:84-89.


Ramos, C. and Napoleão, P. and Fondinho, C. and Selas, M. and Mota Carmo, M. and Cruz Ferreira, R. and Pinheiro, T. Expansive growth of atherosclerotic plaques assessed by VH-IVUS: Association with TNF-α and OX-LDL levels in circulation: CARDIOTECHNIX 2013 - Proceedings of the International Congress on Cardio-vascular Technologies 2013; pp:90-94.