As part of the European UroPrint project, iBB-Institute for Bioengineering and Biosciences researchers Teresa Mendes, Maria Catarina Carreira, Ana Fernandes-Platzgummer, and Cláudia Lobato da Silva recently reported the establishment of a xeno(geneic)-free culture platform for smooth_muscle cells envisioning bladder tissue engineering strategies.

✅ This study establishes a scalable and clinically relevant manufacturing process – 𝐟𝐫𝐨𝐦 𝐢𝐬𝐨𝐥𝐚𝐭𝐢𝐨𝐧 𝐭𝐨 𝐞𝐱𝐩𝐚𝐧𝐬𝐢𝐨𝐧 – using gamma-irradiated human platelet lysate as a xeno-free culture medium supplement.

✅The team successfully confirmed the smooth muscle-like phenotype of the expanded cells and implemented a plastic microcarrier-based spinner flask system, enabling large-scale cell production for future therapeutic applications.

💡 This research paves the way for more efficient and clinically viable strategies in regenerative_medicine, bringing us closer to advanced bladder tissue engineering solutions.

Link to publication: https://lnkd.in/dKTT4NGu