International Invited Oral Communications 2012
Aires-Barros, M.R., “Aqueous two-phase systems: a new platform for biopharmaceuticals purification”, 6th International Meeting on Biotechnology | BioSpain2012, Bilbao, Spain, September 2012
Aires-Barros, M.R., “Aqueous two-phase systems: a new platform for biopharmaceuticals purification”, invited lecture in the series of department lectures of the Department of Biochemical and Chemical Engineering, Dortmund University, Germany, April 2012
Cabral, J.M.S., “Stem Cell Engineering for Cellular Therapies”, Stem cells and metabolism symposium at Institute of Biomedical Engineering Metabolic Technology Network, Imperial College, London and the Cell Control in a Petri Dish (CCPD) Collaborative Network, Nottingham, UK, November 2012
National Invited Oral Communications 2012
Cabral. J.M.S., “Avanços da Biotecnologia em Portugal”, Conferência OeirasBioTech, Oeiras, Portugal, March 2012
da Silva, C.L., “Células Estaminais e Cartilagem”, 4th Workshop on Articular Cartilage, Lisbon, November 2012
de Carvalho, C.C.C.R., “Taking advantage of bacterial adaptation to the marine environment”, Jornadas do Centro de Investigação CB3 (Biologia, Biotecnologia e Biomedicina), Lisbon, Portugal, June 2012
Fernandes T.G., "High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research", Workshop Nano12 - Shaping the Future, Lisbon, October 2012
Fernandes, P., “Enzyme immobilization: more than a one-trick pony”, Jornada do Centro de Investigação CB3, Lisbon, June 2012
Fernandes, P., “Miniaturização em Biotecnologia: promessas, realidades e perspetivas”, XV Jornadas de Engenharia Biológica, Braga, November 2012
Ferreira AS, Silva IN, Becker JD, McClean S, Callaghan M, Moreira LM., “Involvement of the BceF tyrosine kinase in stress response, biofilm formation and virulence in Burkholderia cepacia IST408 clinical isolate”, XXXVII Jornadas de Genética, Lisboa, Portugal, (2012).
Fialho A.M. “Bacterial proteins, a new class of multifunctional anticancer drugs” 3rd PhD Meeting ITQB, 10-12 Outubro, Oeiras, Portugal, 2012
Marques, M.P.C., de Carvalho, C.C.C.R., “Bactérias produtoras de sideróforos”, Conferência “Baia do Seixal – Estuário do Tejo – A importância dos Ecossistemas Aquáticos”, Seixal, November 2012
Palma, M., Madeira, S. C., Mendes-Ferreira, A. and Sá-Correia, I., Impact of assimilable nitrogen availability in glucose uptake kinetics in Saccharomyces cerevisiae during alcoholic fermentation. XIX Jornadas de Biologia de Leveduras Professor Nicolau van Uden, Lisbon, Portugal, 15-16 June 2012
Prazeres, D.M.F., “Biomimetismo: Inovação inspirada na vida marinha”, inauguration session of the exhibition “Biomimicry: Innovation inspired by marine life”, Vasco da Gama Aquarium, Lisbon, November 2012
Sá-Correia, "Systems-based understanding of chemical stress defense mechanisms in yeast: challenges and opportunities", António V. Xavier Seminars, ITQB, Oeiras, 29th Nov, 2012
Santhagunam, S., dos Santos, F., Madeira, C., Salgueiro, J., Cabral, J.M.S., “In vitro expansion of Synovial Mesenchymal Stem Cells”, 4th workshop on Articular Cartilage, Lisbon, November 2012
Silva IN, Ferreira AS, Becker JD, Tavares AC, Moreira LM., “Genotype and phenotype variation of Burkholderia multivorans sequential isolates during long-term colonization of the airways of cystic fibrosis patients”, XXXVII Jornadas de Genética, Lisboa, Portugal, (2012).
International Oral Communications 2012
Andrade, P.Z., dos Santos, F., Almeida-Porada, G., da Silva, C.L., Cabral, J.M.S., "Bioengineering approaches for the optimization of the ex-vivo expansion of hematopoietic stem/progenitor cell for cell therapy", 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
Andrade, P.Z., dos Santos, F., Almeida-Porada, G., da Silva, C.L., Cabral, J.M.S., “Bioengineering approaches for the optimization of the ex-vivo expansion of hematopoietic stem/progenitor cell for cell therapy”, 3rd International Conference on Stem Cell Engineering | ICSCE 2012, Seattle, USA, April-May 2012
Andrade, P.Z., dos Santos, F., Almeida-Porada, G., da Silva, C.L., Cabral, J.M.S., “Towards optimal culture conditions for the ex-vivo expansion of umbilical cord blood hematopoietic stem/progenitor cells for cell therapy”, 243rd ACS National Meeting – Chemistry of Life, San Diego, USA, March 2012
Azevedo, A.M., Aires-Barros, M.R., “Aqueous two-phase systems for antibodies purification: from macro to micro-scale”, Recovery of Biological Products XV, Stowe (VT), USA, July – August 2012
Azevedo, A.M., Aires-Barros, M.R., “Revisiting aqueous two-phase extraction for antibodies purification: from a mixer settler battery to microfluidic devices”, 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
Badenes, S.M., Lemos, F., Cabral, J.M.S., “Continuous biodiesel production in a cutinase membrane bioreactor”, 243rd ACS National Meeting – Chemistry of Life, San Diego, USA, March 2012
Barbosa, H.S.C., Fernandes, T.G., Dias, T.P., Diogo, M.M., Cabral, J.M.S., "Multifactorial analysis of embryonic stem cell self-renewal reveals a crucial role of GSK-3-mediated signaling at physiological oxygen levels”, 243rd ACS National Meeting – Chemistry of Life, San Diego, USA, March 2012
Barbosa, H.S.C., Meli, L., Diogo, M.M., Linhardt, R.J., Cabral, J.M.S., Dordick, J.S., “Three-dimensional neural stem cell culture microarray for high-throughput studies of neuronal differentiation and toxicology”, 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
Borlido, L., Moura, L., Azevedo, A.M., Roque, A.C.A., Farinha, J.P.S., Aires-Barros, M.R., “Thermo-responsive magnetic particles in antibody separation”, 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012 [Keynote lecture]
Buziol, S., Menezes, J.C., “Combination of spectroscopic methods for Inline-monitoring and control of mammalian cell cultivations, IFPAC Annual Meeting 2012, Baltimore, Maryland, USA, January 2012
Carvalho, R.Jr., Woo, J., Azevedo, A.M., Cramer, S.M., Aires-Barros, M.R., “Phenyl boronic acid as ligand for a multimodal chromatography”, 32th International Symposium on the Separation of Proteins, Peptides and Polynucleotides | ISPPP, Istanbul, Turkey, September 2012
Costa, AC, Pires C, Henriques A, Camacho G, Cabrito T, Sá-Correia I, Teixeira MC, CgQdr2 drug:H+ antiporter from the pathogenic yeast Candida glabrata: role and regulation in azole drug resistance, XIX Jornadas de Leveduras Prof. Nicolau van Uden, 15-16 Jun 2012, Caparica, Portugal.
da Fonseca, M.M.R., Cavalheiro, J.M., de Almeida, C.D., de Carvalho, C.C.C.R. , Cesário, T., Raposo, R., Pollet, E., Diogo, H., “Upgrade of waste glycerol to short-chain polyhydroxyalkanoates co-polymers”, Environmental, Microbiology & Biotechnology in the frame of the knowledge-Based Bio & Green Economy | EMB2012, Bologna, Italy, April 2012
da Silva, C.L., Andrade, P.Z., dos Santos, F., Almeida-Porada, G., Cabral, J.M.S., “Bioengineering approaches for the optimization of the ex-vivo expansion of hematopoietic stem/progenitor cells for cell therapy”, 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
da Silva, C.L., dos Santos, F., Andrade, P.Z., Abecasis, M.A., Gimble, J., Campbell, A., Boucher, S., Roos, E., Kuligowski, S., Chase, L., Vemuri, M., Cabral, J.M.S., “Scalable expansion of human mesenchymal stem cells using a microcarrier-based system under serum-free and xeno-free conditions”, Scale-Up and Manufacturing of Cell-Based Therapies, ECI, San Diego, California, USA, January 2012
de Barros, D.P.C., Campos, S.R.R., Madeira, P.P., Azevedo, A.M., Baptista, A.M., Aires-Barros, M.R., “Prediction of protein partitioning in aqueous two-phase system using a semi-empirical approach”, 32th International Symposium on the Separation of Proteins, Peptides and Polynucleotides | ISPPP, Istanbul, Turkey, September 2012
de Carvalho, C.C.C.R., “Production of energy with bacterial cells”, 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
de la Vega, J., Monteiro, G.A., Prazeres, D.M.F., “Impact of plasmid quality on lipoplex mediated transfection”, 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
dos Santos, F., Andrade, P.Z., Abecasis, M.A., Gimble, J., Campbell, A., Boucher, S., Roos, E., Kuligowski, S., Chase, L., Vemuri, M., da Silva, C.L., Cabral, J.M.S., “Scalable expansion of human mesenchymal stem cells using a microcarrier- based system under serum-free and xeno-free conditions”, 243rd ACS National Meeting – Chemistry of Life, San Diego, USA, March 2012
dos Santos, F., da Silva, C.L., Andrade, P.Z., Abecasis, M.M., Gimble, J., Campbell, A., Boucher, S., Roos, E., Kuligowski, S., Chase, L.,Vemuri, M., Cabral, J.M.S., “Scalable expansion of human mesenchymal stem cells using a microcarrier-based system under serum-free and xeno-free conditions", 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
Gil, F.N., Gonçalves, A.C., Bëcker, J.D., Viegas, C.A., “Pesticide toxicity studies using gene expression profiling in the model yeast Saccharomyces cerevisiae”, 7th European Conference on Pesticides and Related Organic Micropollutants in the Environment & 13th Symposium on Chemistry and Fate of Modern Pesticides”, Porto, Portugal, October (2012)
Gonçalves, G.A.L., Prather, K.L.J., Monteiro, G.A., Prazeres, D.M.F., “Rational engineering of Escherichia coli strains for improved manufacturing of plasmid biopharmaceuticals”, Protein and Antibody Engineering Summit, Viena, Austria, November 2012
Hakemeyer, C., Strauss, U., Jose, G.E., Folque, F., Menezes, J.C., “Developing scale-independent NIR calibrations for PAT monitoring of mab cultivations during development and manufacturing”, IFPAC Annual Meeting 2012, Baltimore, Maryland, USA, January 2012
Hakemeyer, C., Strauss, U., Jose, G.E., Folque, F., Menezes, J.C., “Predicting MAb product yields using near-infrared and 2D-fluorescence spectra of cultivation media components”, IFPAC Annual Meeting 2012, Baltimore, Maryland, USA, January 2012
Marques, M.P.C., Fernandes P., de Carvalho, C.C.C.R., “From the ocean to the market: filling the gap”, International Meeting on Marine Resources | IMMR’12, Peniche, Portugal, May 2012
Matos, R.G., Fialho, A.M., López-Viñas, E., Gomez-Puertas, P. Schuster, G., Arraiano, C.M. “The evolution of the RNase II-family of exoribonucleases: singular features in Archaea and Cyanobacteria” FASEB Meeting: Post-transcriptional control of gene expression: mechanisms of mRNA decay, June 24-29, Steamboat Springs, Colorado, 2012
Meli, L., Barbosa, H.S.C., Diogo, M.M., Linhardt, R.J., Cabral, J.M.S., Dordick, J.S., “Three-dimensional cellular microarray platform for human neural stem cell differentiation and toxicology studies”, 243rd ACS National Meeting – Chemistry of Life, San Diego, USA, March 2012
Menezes, J.C., Sacher, S., Scharrer, G., Leitgeb, S., Voura, C., Fraser, S.D., Khinast, J.G., “A pharmaceutical engineering process/product life-cycle approach to drug product development and manufacturing”, AIChE Annual Meeting 2012, Pittsburgh, USA, October 2012
Oliveira, P.H., da Silva, C.L., Cabral, J.M.S., “An appraisal of human mtDNA instability: role of DNA topology and sequence motifs”, 15th European Congress on Biotechnology-Biocrossroads, Istanbul, Turkey, September 2012
Raiado-Pereira, L., de la Vega, J., Mateus, M., Monteiro, G.A., Prazeres, D.M.F., “Efficiency of transient transfection in a mammalian cell model influenced by pDNA purification by membrane-HIC”, 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
Ramos C.G., A.M. Grilo, P.J.P. da Costa, J. R. Feliciano, J.H. Leitão*, “Towards the unveiling of the biological roles played by small non-coding RNAs in the opportunistic pathogens of the Burkholderia cepacia complex”. FEBS International Workshop “New Developments in RNA Biology”. 1-4 September, Tavira, Portugal, 2012.
Rodrigues, C.A.V., Diogo, M.M., da Silva, C.L., Cabral, J.M.S., “Design and operation of a bioreactor system for the expansion pf mouse embryonic stem cell-derived neural stem cells on microcarriers”, 243rd ACS National Meeting – Chemistry of Life, San Diego, USA, March 2012
Rodrigues, C.A.V., Diogo, M.M., da Silva, C.L., Cabral, J.M.S., “Design and operation of a bioreactor system for the expansion of mouse embryonic stem cell-derived neural stem cells on microcarriers”, 9th European Symposium on Biochemical Engineering Science | ESBES, Istanbul, Turkey, September 2012
Sacher, S., Wahl, P., Markl, D., Treffer, D., Menezes, J.C., Koscher, G., Roblegg, E., Khinast, J.G., “PAT for pharmaceutical extrusion monitoring and supervisory control”, AIChE Annual Meeting 2012, Pittsburgh, USA, October 2012
Schewitz, J., Herdling, T., Lochmann, D., Reich, G., Menezes, J.C., “QbD: A case-study from an industrial pharmaceutical fluid bed granulation”, IFPAC Annual Meeting 2012, Baltimore, Maryland, USA, January 2012
Schewitz, J., Herdling, T., Lochmann, D., Reich, G., Menezes, J.C., “Comparison of different techniques for determination of particle size distributions of pharmaceutical granules, IFPAC Annual Meeting 2012, Baltimore, Maryland, USA, January 2012
Simões, I.N., Boura, J., dos Santos, F., Andrade, P.Z., Cardoso, C., da Silva, C.L., Cabral, J.M.S., “Isolation and characterization of mesenchymal stem cells from umbilical cord matrix ising a fully defined serum-/xeno-free system”, Biomedical Engineering Society Annual Meeting | BMES 2012, Atlanta, USA, October 2012
Teixeira MC, Systematic functional analysis of the drug:H+ antiporter family from the pathogenic yeast C. glabrata, Yeast Genetics and Molecular Biology Meeting, July 31 - August 5 2012, Princeton, NJ, USA.
Viegas, C.A., Chelinho, S., Moreira-Santos, M., Silva, V., Mateus, C., Ribeiro, R., Fialho, A.M., Sousa, J.P. “Pseudomonas sp. strain ADP as a bioaugmentation bacterium in soil microcosms contaminated with herbicidal formulations containing s-triazines”, Symposium on Pollutant degradation under environmental stress: towards rational bioaugmentation - BACSIN2012, Amsterdam, Netherlands, 29-30 Mar, 2012
Viegas, C.A., Chelinho, S., Silva, V., Mateus, C., André, S., Moreira-Santos, M., Viana, P., Ribeiro, R., Fialho, A.M., Sousa, J.P., “Performance of a bioremediation tool based on Pseudomonas sp. strain ADP in soils contaminated with s-triazine herbicides”, 7th European Conference on Pesticides and Related Organic Micropollutants in the Environment & 13th Symposium on Chemistry and Fate of Modern Pesticides – Pesticides 2012, Porto, Portugal, October (2012)
National Oral Communications 2012
Barbosa, H.S.C., Fernandes, T.G., Dias, T.P., Diogo, M.M., Cabral, J.M.S., “Multifactorial analysis of embryonic stem cell self-renewal a crucial role of GSK-3-mediated signaling under hypoxia”, 3rd Meeting of the Institute for Biotechnology and Bioengineering (IBB), Lisbon, Portugal, March 2012
Dalila Mil-Homens and Arsénio M. Fialho “Trimeric autotransporter adhesins in the human pathogen Burkholderia cenocepacia: a multifunctional family of proteins implicated in virulence” 3rd Scientific Meeting of Institute for Biotechnology and Bioengineering, 16-17 Março, Instituto Superior Técnico, Lisboa, 2012
de Carvalho, C.C.C.R., Marques, M.P.C., Fernandes, P., “Taking advantage of bacterial adaptation to the marine environment”, 3rd Meeting of the Institute for Biotechnology and Bioengineering (IBB), Lisbon, Portugal, March 2012
Dias PJ, Sá-Correia I, Evolution of the 12-spanner drug:H+ antiporters of family 1 (DHA1) in the pathogenic Candida species: phylogenetic analysis of Mdr1 and Flu1 proteins, XIX Jornadas de Biologia de Leveduras “Nicolau van Uden”, Campus da Caparica, Portugal, 15-16 June, 2012.
dos Santos, F., Andrade, P.Z., Abecasis, M.M., Gimble, J., da Silva, C.L., Cabral, J.M.S., “A serum-free and xeno-free microcarrier-based scalable system for the expansion of human mesenchymal stem/stromal cells”, 7th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Porto, Portugal, April 2012
Fernandes, P., Marques, M.P.C., de Carvalho, C.C.C.R., Cabral, J.M.S., “The role of microreactors in the development of bioconversion processes”, 3rd Meeting of the Institute for Biotechnology and Bioengineering (IBB), Lisbon, Portugal, March 2012
Ferreira, A.S., Silva, I.N., Becker, J.D., McClean, S., Callaghan, M., Moreira, L.M., “Involvement of BceF tyrosine kinase in stress response, biofilm formation and virulence Burkholderia cepacia IST408 clinical isolate”. XXXVII Jornadas Portuguesas da Genética, Lisbon, Portugal, May (2012);
Fonseca, M.D., de Carvalho, C.C.C.R., “Monitoring bacterial performance using fluorescence microscopy”, XLVI Congress of the Portuguese Society for Microscopy | SPMicros 2012, Lisbon, Portugal, September 2012
Goncalves, G.A.L., Prather, K.L.J., Monteiro, G.A., Prazeres, D.M.F., “De novo creation of MG1655-derived E. coli strains specifically designed for plasmid DNA production”, 3rd Meeting of the Institute for Biotechnology and Bioengineering (IBB), Lisbon, Portugal, March 2012
Madeira, A., da Silva, C.L., dos Santos, F., Cabral, J.M.S., Sá-Correia, I., “Human mesenchymal stem cells expression program upon extended ex-vivo cultivation, as revealed by 2-DE-based quantitative proteomics”, 7th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Porto, Portugal, April 2012
Marques, M.P.C., de Carvalho, C.C.C.R., “Bactérias produtoras de sideróforos”, Conferência “Baia do Seixal – Estuário do Tejo – A importância dos Ecossistemas Aquáticos, Seixal, Portugal, November 2012
Nunes, M.A., Fernandes, P.C., Ribeiro, M.H.L., “Process engineering and operational stability of PVA-naringinase - comparative studies between microtiter, parallel stirred and packed bed reactor system”, 4th Postgraduate iMed.UL Students Meeting, Lisbon, Portugal, December 2012
Nuno P. Mira, Involvement of the Haa1p-dependent regulatory network in S. cerevisiae response to acetic acid stress: genome-wide approaches guided by bioinformatic analysis, 1st symposium in Bioinformatics, Universidade de Trás-os-Montes e Alto Douro, 15th February, (2012)
Oliveira, P.H., Lobato da Silva, C., Cabral, J.M.S., “An appraisal of human mtDNA instability: role of DNA topology and composition”, 3rd Meeting of the Institute for Biotechnology and Bioengineering (IBB), Lisbon, Portugal, March 2012
Santos MR, Marques AT, Becker JD, and Moreira LM. (2012). Involvement of the TetR transcriptional regulator SMc03169 in pH sensitivity and contribution to nodulation competitiveness in Sinorhizobium meliloti. 3rd Meeting of the Institute for Biotechnology and Bioengineering, Lisbon, Portugal.
Silva, I,N,, Ferreira, A.S., Becker, J.D., Tavares, A.C., Moreira, L.M., “Genotype and phenotype variation of Burkholderia multivorans sequential isolates during long-term colonization of the airways of cystic fibrosis patients”. XXXVII Jornadas Portuguesas da Genética, Lisbon, Portugal, May (2012);
Simões, I.N., Boura, J., dos Santos, F., Andrade, P.Z., Cardoso, C., da Silva, C., Cabral, J.M.S, “Successful isolation and ex-vivo expansion of human mesenchymal stem cells from the umbilical cord matrix under serum-/xeno-free culture conditions”, 7th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, Porto, Portugal, April 2012
Viegas, C.A., Chelinho, S., Silva, V., Mateus, C., André, S., Moreira-Santos, M., Viana, P., Ribeiro, R., Fialho, A.M., Sousa, J.P., “Performance of a bioremediation tool based on Pseudomonas sp. strain ADP in soils contaminated with s-triazine herbicides”, 7th European Conference on Pesticides and Related Organic Micropollutants in the Environment & 13th Symposium on Chemistry and Fate of Modern Pesticides – Pesticides 2012, Porto, Portugal, 7-10 Oct, 2012
