M.Sc. Thesis - 2014

 

Ana Alexandra Navarro Rodrigues, MSc in Bioengineering and Nanosystems “Characterization of gellan-like polymers for new biotechnological applications”.. Supervisors: Leonilde F. M. Moreira, Frederico C. A. Ferreira (2014).
 
Ana Catarina dos Reis Faria, MSc in Biotechnology, “Development of Rapid Tests for the Detection of L-malic Acid in Wine Using Enzymes Immobilized on Paper via Carbohydrate-binding Modules”, UL/IST (Supervisor: D. M. F. Prazeres).
 
Ana Cláudia Teixeira Castanheiro, MSc in Biological engineering, “A comparative study between biomagnetic analysis and scanning electron microscopy of particulate matter deposition on urban green”, UL/IST.(Supervisors: Carla C. C. R. de Carvalho, Roeland Samson)
 
Ana Lúcia Bulário Morais, MSc in Biological Engineering, “Definição e implementação de estratégias de melhoria contínua no processo produtivo de margarinas”, UL/IST (Supervisors: M. Mateus, C. I. C. Pinheiro)
 
Ana Mafalda Marques Cardoso, MSc in Bioengineering and Nanosystems “Caracterização de populações microbianas em células de combustível para a produção de bioelectricidade.. Supervisors: Jorge H. G. Leitão (2014).
 
Ana Margarida Couras dos Santos, MSc in Biological Engineering, “Projecto de melhoria contínua: aumento da ‘Eficiência Global dos Equipamentos’ e da capacidade instalada numa linha de produção alimentar”, UL/IST (Supervisors: M. Mateus, C. Faustino)
 
Ana Raquel Pina Porteira, MSc in Biomedical Engineering, “Rett Syndrome Modelling from Human Induced Pluripotent Stem Cells Using a Monolayer Culture System”, UL/IST. (Supervisors: M. M. Diogo, T. G. Fernandes).
 
Ana Sofia Santos Sousa, MSc in Biological Engineering, “Produção microbiana de lípidos e carotenóides em culturas da levedura Rhodosporidium toruloides NCYC 921 desenvolvidas em regime semi-descontínuo”, UL/IST (Supervisors: José A. L. Santos, Teresa Lopes da Silva (LNEG))
 
André Nunes dos Santos Nascimento, “Polishing of Monoclonal Antibodies Stream through Convective Flow Devices”, MSc in Biotechnology, Instituto Superior Técnico, 2012-2013 (supervisor: Ana Azevedo)
 
Andreia Sofia Santana dos Santos, MSc in Biomedical Engineering, “Comprehensive characterization of human mesenchymal stem/stromal cells from healthy donors and acute myocardial infarction patients” (Supervisors: C. Lobato da Silva, Joaquim M. S. Cabral)
 
Antonio Carlos Martins de Jesus Lima Grilo, "Aqueous Two-Phase Systems for Large Scale Purification of Monoclonal Antibodies”, MSc in Biological Engineering, Instituto Superior Técnico, 2012-2013 (supervisor: Ana Azevedo)
 
António Pedro Lopes Páscoa Ramos, MSc in Biological Engineering, “Effect of cell wall modifying enzymes on the rheological behaviour of citrus fibres dispersions”, UL/IST (Supervisors: M. Mateus, H. van der Hijden)
 
Carlos Júnio Caridade Rodrigues, MSc in Biotechnology, “The importance of lipids to biofilm formation”, UL/IST (Supervisor: Carla C.C.R. de Carvalho)
 
Catarina Alexandra Simões Prata, MSc in Biotechnology “Studies on the involvement of the yeast ABC transporter Pdr18 in acetic acid tolerance at temperatures in the range 30-40°C”.. Supervisor: Isabel M. Sá-Correia. (2014).
 
Catarina Benavente Perdigão, MSc in Biotechnology. “Azurin interferes with lipid raft organization by decreasing the membrane protein caveolin – 1”.. Supervisors: Arsénio C. S. M. Fialho; Nuno F. S. Bernardes (2014).
 
Cátia Isabel Pereira Jorge, MSc in Biotechnology, “Development of novel biomimetic affinity adsorbents for plasmid DNA purification”, UL/IST (Supervisors: M. A. Taipa, D. M. F. Prazeres)
 
Cláudia de Sousa Medeiros Cordeiro, MSc in Biological Engineering, “Scalable Expansion of Human Induced Pluripotent Stem Cells (hiPSC) under Xeno-free Conditions”, UL/IST (Supervisors: M. M. Diogo, T.G. Fernandes).
 
Cláudia Patrícia Almeida Alves, MSc in Biological Engineering “Development of a method for the purification of minicircles”, (Supervisors: D. M. F. Prazeres, G. A. Monteiro)
 
Diana Sofia Cardoso Marques, MSc in Biotechnology, “Construction of Escherichia coli strains for higher plasmid production: Evaluation of lon gene knockout and implementation of a marker-free system”, (Supervisors: G. A. Monteiro, D. M. F. Prazeres)
 
Diana Varandas da Cunha, MSc in Biotechnology “Molecular mechanisms underlying tolerance to acetic acid in vaginal Candida glabrata clinical isolates: role of the CgHaa1-dependent system”.. Supervisor: Nuno G. P. Mira (2014).
 
Dina de Jesus Marinheiro Antunes, MSc in Biotechnology, “Downstream processing of cell culture-derived animal viruses, UL/IST (Supervisors: M. R. Aires-Barros, M. Fevereiro)
 
Eduarda Isabel Anacleto Espadinha, MSc in Biological Engineering, “Depicting the mechanism of action of an ATMP for the development of the potency assay”, UL/IST (Supervisors: C. Lobato da Silva, Francisco dos Santos)
 
Emanuel Filipe Alves Lopes, MSc in Biological Engineering, “Development of an online method for determination of the apparent viscosity inside stirred tank reactors” UL/IST (Supervisors: José A. L. Santos, Martin Wunderlich (RWTH Aachen))
 
Fábio Daniel Anastácio Gonçalves, MSc in Biotechnology, “Influence of the cell membrane on bacterial resistance and persistance”, UL/IST (Supervisor: Carla C.C.R. de Carvalho)
 
Filipa Martins Ribeiro, MSc in Biological Engineering, “Generation of liver specific endothelial cells for co-culture with hepatocytes”, UL/IST, (Supervisors: M. M. Diogo, R. Boon).
 
Filipa Vieira de Sousa, MSc in Biological Engineering, “The influence of surface chemistry on osteogenic differentiation of hMSCs, UL/IST (Supervisors: C. Lobato da Silva, L. Moroni)
 
Gonçalo Nuno Barata Fonte, MSc in Biological Engineering, “The effect of key process parameters on human mesenchymal stem cell expansion and harvest”, UL/IST (Supervisors: C. Lobato da Silva, Qasim Rafiq)
 
Inês Daniela Marques Graça, MSc in Biological Engineering, “Aumento de escala de produção e ajustes nas especificações de uma nova bolacha”, UL/IST (Supervisors: M. Mateus, L. Bernardino)
 
Inês Pinto Ferreira, "Novel capture processes for monoclonal antibodies purification", MSc in Biological Engineering, Instituto Superior Técnico, 2012-2013 (supervisor: Ana Azevedo)
 
Isabel Cardoso Alves de Campos Pinto, “Clarification and capture of monoclonal antibodies from complex media using aqueous two-phase systems”, MSc in Biotechnology, Instituto Superior Técnico, 2013-2014 (supervisior: Ana Azevedo)
 
Joana Anastácio Ramos, MSc in Bioengineering and Nanosystems, “Experimental Study of the Transport of Micro-droplets by Electrostatic Actuation”, UL/IST (supervisors: Ana Moita, D. M. F. Prazeres).
 
Joana Catarina Capinha de Matos, MSc in Biomedical Engineering, “Design and production of silica and ORMOSIL nanoparticles for gene delivery”, UL/IST (Supervisors: M. C. Gonçalves, G. A. Monteiro)
 
Joana Rita Mendes Tavares, “Mitochondria function and biogenesis on Oligodendrocyte Precursor Cells differentiation in vitro”, UL/IST, (Supervisors: M.M. Diogo and Ana Amaral).
 
João Mateus, MSc in Biological Engineering, “Towards a High-throughput Microfluidic Drug Discovery Platform for the Screening of GPCR Targets in Cells”, UL/IST (Supervisors: J. P. Conde, D. M. F. Prazeres).
 
José António Vieira Rodrigues, MSc in Biotechnology,“Role of the transcription factor Haa1p and Haa1p-mutant-proteins in yeast response to acetic acid: focus on mRNA levels from TPO2, HSP30 and HRK1, intracellular ATP levels and pHi”. Supervisor: Isabel M. Sá-Correia (2014).
 
José Pedro Aranha Carvalho dos Santos, MSc in Biological Engineering, “Membrane-based purification of viral particles”, UL/IST (Supervisors: M. Mateus, L. Villain)
 
Liliana Isabel Casimiro Brito, MSc in Biotechnology, “Minicircle production and delivery to human mesenchymal stem/stromal cells for angiogenesis stimulation”, (Supervisors: G. A. Monteiro, C. Madeira)
 
Luca Bronzato, Bioreactor for Stem Cell Expansion: Theoretical Design, Modelling of Mass Transfer and Experimental Evaluation of a Stirred Vessel (Dez 2014). Corso di laurea magistrale (CLM) in Ingegneria Biomedica, Politecnico di Milano, Scuola di Ingegneria Industriale e dell'Informazione, Relatori: Sara Mantero, Frederico Ferreira, Correlatori: Vítor Geraldes, Ing. Ilaria Stefani
 
Maike Coelho Afonso Gomes, MSc in Biomedical Engineering, “Inverted colloidal crystal scaffolds based on a biodegradable polyester for cartilage tissue engineering: production, physico-chemical characterization, and in vitro evaluation”, UL/IST (Supervisors: C. Lobato da Silva, J. A. Silva)
 
Marcelo da Silva Ferreira, MSc in Biological Engineering, “The effect of mechanical loading on the viability of skeletal muscle cells”, UL/IST (Supervisors: C. Lobato da Silva, C. Pennisi)
 
Márcia Ferreira Antunes, "Production of recombinant human xanthine oxidase in E. coli and optimization of its application for preparative synthesis of oxidized drug metabolites", MSc in Biological Engineering, Instituto Superior Técnico, 2012-2013 ((supervisor: Ana Azevedo)
 
Maria Alexandra Vieira Marcelino, MSc in Molecular Biology and Genetics, “Efeitos do enriquecimento em oxigénio e da fonte de carbono em operação em biorreactor na produção de pDNA numa estirpe de Escherichia coli”, FC-UL (Supervisors: M. Mateus, R. Zilhão)

Maria Constança de Magalhães Ilharco Cornélio da Silva, MSc in Biological Engineering, “Pilot scale purification of Food Enzymes with Expanded Bed Chromatography”, UL/IST (Supervisors: D. M. F. Prazeres, G. Ferreira)
 
Maria Inês Baptista Leite, MSc in Biological Engineering, “Optimization of culture conditions for artificial blastocysts”, UL/IST (Supervisors: M. M. Diogo, E. Vrij)
 
Maria João Pardelha da Cruz, MSc in Biological Engineering, “Using Drosophila to study regulation of neural stem cell quiescence by nucleocytoplasmic transport”, UL/IST, (Supervisors: M. M. Diogo, Rita Sousa-Nunes).
 
Marta Alexandra Freire Alves, MSc in Biological Engineering, “Effect of cultivation conditions on antimicrobial production in Lactococcus lactis”, UL/IST (Supervisors: D. M. F. Prazeres, F. C. Rodrigues)
 
Micaela Sintra Torrado, MSc in Bioengineering and Nanosystems, “Papel da proteína tirosina fosfatase BceD na interação com Burkholderia e células epiteliais”.. Supervisor: Leonilde F. M. Moreira (2014).
 
Nicole Martins Rodrigues, MSc in Biotechnology, “Exploring Saccharomyces cerevisiae to improve microbe-based production of itaconic acid”.. Supervisor: Nuno G. P. Mira (2014).
 
Nuno Filipe Depetri Araújo, MSc in Biological Engineering, “Development of a mathematical model for the calculation of the CER in a RAMOS device”, UL/IST (Supervisors: P. Fernandes, A. Schulte).
 
Pedro Henrique Magalhães Fernandes Pais, MSc in Biotechnology. “Membrane proteome-wide response to the antifungal drug clotrimazole in Candida glabrata: role of the transcription factor CgPdr1 and the Drug:H+ Antiporters CgTpo1_1 and CgTpo1_2”.. Supervisor: Miguel N. P. C. Teixeira (2014).
 
Raquel Alexandra Ribeiro dos Santos, “An alternative capture step for monoclonal antibodies: phenylboronate as a new multi-modal ligand”, MSc in Biotechnology, Instituto Superior Técnico, 2012-2013 (supervisior: Ana Azevedo)
 
Ricardo Jorge Carvalho Correia, MSc in Biological Engineering, “Influence of Physical and Chemical Treatments on Cell Survival and Acquisition of Pluripotency”, UL/IST (Supervisors: C. Lobato da Silva, Petra de Sutter)
 
Rita Alexandra Martins Caeiro, MSc in Biological Engineering, “Antioxidant effect of caffeic acid alkyl esters in sunflower oil and their combination with other antioxidants”, UL/IST (Supervisors: M. Mateus, I. Hradkova)
 
Rita Azevedo Fernandes, MSc in Biotechnology, “The impact of zwf overexpression on plasmid biopharmaceutical production by Escherichia coli”, IT/UL, (Supervisor: G. A. Monteiro)
 
Rita Romeu Pedreira, MSc in Civil Engineering “Bio-cimentação de solos arenosos para melhoramento das suas características hidro-mecânicas”, IST/UL, (Supervisors: R. Cardoso, G. A. Monteiro)
 
Samuel Duarte Jorge, MSc in Bioengineering and Nanosystems, “Expansion of multipotent mesenchymal stromal cells on gelatin coated alginate microcarriers”, UL/IST (Supervisors: F. C. Ferreira, J.M.S. Cabral)
 
Sandra Cristina da Silva Bernardo, “LYTAG-driven Integrative Platform for Purification of Monoclonal Antibodies by Aqueous Two-phase Systems”, MSc in Biotechnology, Instituto Superior Técnico, 2012-2013 (co-supervision)
 
Sara Isabel da Conceição Dias, MSc in Biological Engineering, “Análise e melhoramento dos níveis de qualidade percepcionados pelo consumidor através do controlo interno de variáveis relativas ao processo e ao produto”, UL/IST (Supervisors: M. Mateus, S. Borges)
 
Sara Isabel Fernandes Mateus, MSc in Biotechnology, “Construction of plasmids for Schmallenberg virus proteins expression”, UL/IST (Supervisors: G. A. Monteiro, S. de Barros)
 
Sílvia Filipa Lopes de Matos, MSc in Applied Microbiology. “Functional analysis of RTX proteins of Sinorhizobium meliloti and role in biological nitrogen fixation symbiosis”  Faculdade de Ciências, Universidade de Lisboa. Supervisor: Leonilde Moreira (2014).
 
Sílvia Marina de Jesus Andrade “Production of therapeutic plasmid DNA by lactic acid bacteria”, Mestrado em Biologia Molecular e Genética, FCUL, (Supervisors: G. A. Monteiro, H. Caria) 2014
 
Tiago Miguel da Chica Aguiar, MSc in Biological Engineering, “Integrated strategies for up- and down-stream bioprocessing of human mesenchymal stem cells”, UL/IST (Supervisors: C. Lobato da Silva, Margarida Serra)