Mafalda Cavalheiro

PhD Student

Research Activities

- Mechanisms of antifungal drug resistance in Candida glabrata

- Mechanisms of host-pathogen interactions

- Transcriptomics


Selected Publications


Pais P, Costa C, Cavalheiro M, Romão D, Teixeira MC, "Transcriptional control of drug resistance, virulence and immune system evasion in pathogenic fungi: a cross-species comparison", Frontiers in Cellular and Infection Microbiology, 6: 131, 2016.


Cavalheiro M, Costa C, Pais P, Teixeira MC, Acquisition of resistance to azole antifungal drugs in Candida species: imidazoles versus triazoles, In: “Ketoconazole: Clinical Pharmacokinetics, Uses and Potential Side Effects”, Nova Science Publishers, Inc., NY, USA, vol.8, chapter 9, 2016.


Costa C, Ribeiro J, Miranda IM, Silva-dias AI, Cavalheiro M, Costa-de-oliveira S, Rodrigues AG and Teixeira MC, Clotrimazole drug resistance in Candida glabrata clinical isolates correlates with increased expression of the drug:H+ antiporters CgAqr1, CgTpo1_1, CgTpo3 and CgQdr2. Frontiers in Microbiology 7:526, 2016.


Costa C, Ponte A, Pais P, Santos R, Cavalheiro M, Takashi Y, Chibana H, Teixeira MC, "New mechanisms of flucytosine resistance in C. glabrata unveiled by a chemogenomics analysis in S. cerevisiae", PLoS ONE, 10(8):e0135110, 2015.




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