Joana Rita Rodrigues Feliciano

PhD Student

Research Activities

My research is focused on the understanding of the biological roles played by the Hfq-like RNA chaperones Hfq and Hfq2 from bacteria of the Burkholderia cepacia complex (Bcc) on the regulation of bacterial virulence. Zebrafish embryos are being used as an in vivo infection model to study the roles played by the RNA chaperones on Bcc biology and pathogenesis.


Selected Publications


Feliciano, J.R., Sousa, S.A., Pinheiro, P.F. and Leitão, J.H., “Biochemical and functional studies on the Burkholderia cepacia complex bceN gene, encoding a GDP-D-mannose 4,6-dehydratase”. PLoS One, 8(2):e56902. doi:10.1371/journal.pone.0056902, 2013.


Sousa, S.A., Feliciano, J.R., Grilo, A.M. and Leitão, J.H., “Bioinformatics: a molecular microbiologist’s perspective”, Current Bioinformatics (in press).


Leitão, J.H., Sousa, S.A., Ramos, C.G., Feliciano, J.R., Grilo A.M., Costa, P.J.P., “Experimental and bioinformatics approaches to identify potential targets and develop novel strategies to fight infections caused by multiresistant Burkholderia cepacia complex bacteria”. In: Microbial pathogens and strategies for combating them: science, technology and education (ed. A. Méndez-Vilas), Vol 1 pp 372-383. Formatex Research Center. ISBN (13) Volume 1: 978-84-939843-9-7, 2013.



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