Ana Sílvia Moreira

PhD Student

Research Activities

- Mechanisms of adaptation, persistence and virulence in Burkholderia cepacia complex bacteria
- Bacterial molecular epidemiology and physiology
- Bacterial metabolomics


Selected Publications


Moreira, A.S., Coutinho, C.P., Azevedo, P., Lito, L., Melo-Cristino, J., and Sá-Correia, I. (2014).Burkholderia dolosa phenotypic variation during the decline in lung function of a cystic fibrosis patient during 5.5 years of chronic colonization. Journal of Medical Microbiology. 63: 594-601.


dos Santos, S.C., Mira, N.P., Moreira, A.S., Sá-Correia, I. (2012). Quantitative- and phospho-proteomic analysis of the yeast response to the tyrosine kinase inhibitor imatinib to pharmacoproteomics-guided drug line extension. OMICS: A Journal of Integrative Biology. 16(10): 537-551.


Coutinho, C.P., dos Santos, S.C., Madeira, A., Mira, N.P., Moreira, A.S., Sá-Correia, I. (2011). Long-term colonization of the cystic fibrosis lung by Burkholderia cepacia complex bacteria: epidemiology, clonal variation and genome-wide expression alterations. Frontiers in Cellular and Infection Microbiology, 1 , article 12.


Mira, N.P., Madeira, A., Moreira, A.S., Coutinho, A.P., Sá-Correia, I. (2011). Genomic expression analysis reveals strategies of Burkholderia cenocepacia to adapt to the airways of cystic fibrosis patients and antimicrobial therapy. PLOS One, 6, e28831.


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