Tiago P. Dias
PhD Student
Research
Activities
My topic of studies consists in evaluating the cellular signaling state
of human pluripotent stem cells (hPSCs) and the mechanisms that control
cell fate. Specifically, study the signaling behind the transition
between the pluripotent state and differentiation into neuroectoderm,
mesoderm (cardiomyocytes) and endoderm. The obtained data, conjugated
with modeling approaches and systems biology tools aims to contribute
to optimize and develop new bioengineering processes.
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Selected Publications
Barbosa H.S.C., Fernandes T.G., Dias T.P., Diogo M.M., Cabral J.M.S., "New Insights into the Mechanisms of Embryonic Stem Cell Self-Renewal under Hypoxia: a Multifactorial approach", PLoS ONE, 7(6): e38963 (2012)
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