Irina Neves Simões

PhD Student (MIT|Portugal Program)

Research Activities

I am interested in the field of regenerative medicine and tissue engineering. My work is centered in the development of an in vitro model of urethral sphincter to study stress urinary incontinence. I am interested in the use of decellularization methods to produce organ acellular matrices as a basis for tissue engineering and as well as in the myogenic differentiation potential of mesenchymal stem cells (MSCs) to repopulate the scaffold.


Selected Publications


Simões I.N., Boura J.S., dos Santos F., Andrade P.Z., Cardoso C.M., Gimble J.M., da Silva C.L. and Cabral J.M., “Human mesenchymal stem cells from the umbilical cord matrix: successful isolation and ex vivo expansion using serum-/xeno-free culture media” Biotechnol J. 8 (4) 448-58 (2013).


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