Isabel Campos Pinto

Research Assistant

Research Activities

I work mainly on the downstream processing of monoclonal antibodies (mAbs) through aqueous two-phase systems (ATPS). My goal is to design an innovative downstream process based on ATPS for the purification of mAbs from a complex medium, comprising cell separation and antibody selective extraction, envisaging process integration and intensification.



Selected Publications


Emanuel V. Capela, Isabel Campos-Pinto, Sara A. S. L. Rosa, João A.P. Coutinho, M. Raquel Aires-Barros, Ana M. Azevedo, Mara G. Freire; Development of Integrated Systems for Extraction and Purification of Monoclonal Antibodies directly from CHO Cell Cultures Supernatants using Aqueous Biphasic Systems composed of Ionic Liquids as Adjuvants. 5th PYCheM & 1st EYCheM, 5th Portuguese Young Chemists Meeting and 1st European Young Chemists Meeting (26-29 April 2016, Guimarães, Portugal).

Isabel Campos-Pinto, Sara A.S.L. Rosa, Miguel Arévalo Rodríguez, Ana M. Azevedo and M. Raquel Aires-Barros; Unlocking downstream processing bottleneck: Integrating cell harvest with affinity-enhanced purification of monoclonal antibodies in aqueous two-phase systems using a dual tag ligand. Microbiotec15 – Congress of Microbiology and Biotechnology 2015 (10-12 December 2015, University of Évora, Portugal).

Isabel Campos-Pinto, António Grilo, Edith E. Saloma, Sara A.S.L. Rosa, Ana M. Azevedo, M. Raquel Aires-Barros; Capture of monoclonal antibodies using aqueous two-phase systems. E3 Forum 2014 – Education, Employment and Entrepreneurship (23 and 23 May 2014, Lisboa, Portugal).


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