David José Roxo Botequim

PhD Student (BIOTECnico program)

 

Research Activities

Plasmonic biosensing for clinical diagnosis using spherical gold nanoparticles dimers assembled through DNA hybridization. The preparation of metal nanoparticle dimers is progressing from spherical to rod-shaped particles because these particles can work as optical antennas, providing a way to increase the response signal from biosensors based on fluorescence signaling. Particularly, my research focuses in gold nanorods functionalized with molecular beacons with the objective of sensing specific disease markers, e.g. nucleic acids.

 

Selected Publications

 

Botequim D., Jóskowiak A., Martins S., Prazeres D. M. F., Costa S. M. B., Paulo P M. R., “Functionalized gold nanoparticles for plasmonic biosensing of nucleic acids”, 6th joint congress of Microbiology and Biotechnology: Microbiotec15, Évora, Portugal, December, 2015 (oral communication).

Botequim D., Jóskowiak A., Martins S., Prazeres D. M. F., Costa S. M. B., Paulo P M. R., “Gold nanoparticle dimers for plasmonic biosensing of proteins”, 6th Iberian Meeting on Colloids and Interfaces - RICI6, Guimarães, Portugal, Julho, 2015 (poster communication) 

Botequim D., Maia J., Lino M., Simões P., Ilharco L., Ferreira L., “Nanoparticles and surfaces presenting antifungal, antibacterial and antiviral properties”, Langmuir, 28 (20), pp 7647-7656 (2012).

Henriques C., Vidinha R., Botequim D., Borges J. P., Silva J. A. M. C., “A systematic study of solution and processing parameters on nanofibre morphology using a new electrospinning apparatus”, Journal of Nanoscience and Nanotechnology 9, 3535-3545 (2009). 

Botequim D., Vidinha R., Henriques C., Borges J. P., Silva J. A. M. C., “Production and characterization of chitosan based nanofibres”, 8th World Biomaterials Congress, Amsterdam, Holland, May/June, 2008 (poster communication). .

 

 

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