António
Soure
Ph.D. Student (M.I.T. Portugal Program)
Research Activities
I am interested in the GMP-compliant isolation and expansion of
mesenchymal stem cells (MSC). Due to the potential hurdles of using
fetal bovine serum as supplement of MSC culture media, the scientific
community is looking for alternatives in this regard. Chemically
defined xeno-free culture media are now being commercialized but their
exact composition is not fully disclosed. Human platelet lysate arises
as a potential candidate in solving this issue.
Selected publications
Andrade, P. Z., de Soure, A.M., dos Santos, F., Paiva, A., Cabral, J.M.S., da Silva, C.L. (2013) “Ex vivo expansion of cord blood haematopoietic stem/progenitor cells under physiological oxygen tensions: clear-cut effects on cell proliferation, differentiation and metabolism.” Journal of Tissue Engineering and Regenerative Medicine DOI: 10.1002/term.1731