Sandra Costa dos Santos

Post-Doctoral research fellow

Research Activities

Yeast as an eukaryotic model
Stress response and multidrug resistance
Chemogenomics, transcriptomics, and proteomics
Functional genomics and microbial physiology
Bacterial molecular epidemiology and adaptation
Next Generation Sequencing (NGS) analysis

Selected Publications

dos Santos, S.C., Tenreiro, S., Palma, M., Becker, J. and Sá-Correia, I. (2009). Transcriptomic profiling of the yeast response to quinine evidenced a glucose limitation response attributable to drug-induced inhibition of glucose uptake. Antimicrobial Agents and Chemotherapy 3(12): 5213-23.

dos Santos, S.C. and Sá-Correia, I. (2009). Genome-wide identification of genes required for yeast growth under imatinib stress: vacuolar H+-ATPase function is an important target of this anticancer drug. OMICS: A Journal of Integrative Biology 13(3): 185-98.

Sá-Correia I, dos Santos SC, Teixeira MC, Cabrito TR and Mira NP. Drug:H+ antiporters in chemical stress response in yeast. Trends in Microbiology 17(1): 22-31.

Coutinho, C.P., dos Santos, S.C., Madeira, A., Mira, N.P., Moreira, A.S., and Sá-Correia, I. (2012). Long-term colonization of the cystic fibrosis lung by Burkholderia cepacia complex bacteria: epidemiology, clonal variation and genome-wide expression alterations. Frontiers in Cellular and Infection Microbiology, 1: 1-11.

dos Santos, S.C., Mira, N.P., Moreira, A.S., and Sá-Correia, I. (2012). Quantitative- and phospho-proteomic analysis of the yeast response to the tyrosine kinase inhibitor imatinib to pharmacoproteomics-guided drug line extension. OMICS: A Journal of Integrative Biology, 16(10): 537-551.

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