Paulo Jorge Moura Pinto da Costa Dias
Post-Doctoral research fellow
Research Activities
Molecular Biology, Biochemistry
and Physiology of Saccharomyces
cerevisiae.
Yeast response to
environmental stress and toxicogenomics. Characterization of
transcriptional regulatory networks associated with multidrug
resistance (MDR). Systems biology under a bottom-up approach. Yeast
metabolomics. Gene evolution, identification of gene families and
genome analysis. Evolutionary comparative genomics.
Selected Publications
Dias PJ, Sá-Correia I (2014). Phylogenetic and syntenic analyses of the 12-spanner drug:H+ antiporter family 1 (DHA1) in pathogenic Candida species: evolution of MDR1 and FLU1 genes. Genomics. 104:45-57.
Dias PJ, Sá-Correia I (2013). A common evolutionary origin for the hemiascomycetous 14-spanner drug:H+ antiporters of family 2 (DHA2), the siderophore transporters and the glutathione:H+ antiporters of the ARN and GEX families. BMC Genomics. 14:901
Dias PJ, Seret, M-L, Goffeau A, Sá-Correia I, Baret PV (2010). Evolution of the 12-spanner drug:H+ antiporter DHA1 family in hemiascomycetous yeasts. OMICS: A Journal of Integrative Biology. 14:701-710.
Dias PJ, Teixeira MC, Telo JP, Sá-Correia I (2010). Insights into the mechanisms of toxicity and tolerance to the agricultural fungicide mancozeb in yeast, as suggested by a chemogenomic approach. OMICS: A Journal of Integrative Biology. 14: 211-227.
Teixeira MC, Dias PJ, Simões T, Sá-Correia I (2008). Yeast adaptation to mancozeb involves the up-regulation of FLR1 under the coordinate control of Yap1, Rpn4, Pdr3 and Yrr1. Biochemical Biophysical Research Communications. 367: 249-255.
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