Pedro Fonte
Assistant Professor (UAlgarve)

Research Activities
Development of new drug delivery systems based on colloidal carriers and targeted/controlled delivery of drugs across biological barriers. Expertise on the structural characterization of therapeutic proteins entrapped into micro- and nanocarriers, and on the optimization of freeze-drying of biopharmaceuticals. The areas of scientific interest are diabetes, cancer treatment and tissue engineering and regenerative medicine. Currently, he is the PI of a FCT funded project focused on the development of a topical nanotechnological product for wound healing.

Selected Publications
Júlio A, Caparica R, Costa Lima SA, Fernandes AS, Rosado C, Prazeres DMF, Reis S, Santos de Almeida T, Fonte P (2019) Ionic liquid-polymer nanoparticle hybrid systems as new tools to deliver poorly soluble drugs, Nanomaterials 9(8): 1148, doi: 10.3390/nano9081148

Júlio A, Costa Lima SA, Reis S, Santos de Almeida T, Fonte P (2019) Development of ionic liquid-polymer nanoparticle hybrid systems for delivery of poorly soluble drugs, J Drug Deliv Sci Technol In Press, doi: 10.1016/j.jddst.2019.01.030

Oliveira AI, Pinho C, Fonte P, Sarmento B, Dias ACP, Development, characterization, antioxidant and hepatoprotective properties of poly(Ɛ-caprolactone) nanoparticles loaded with a neuroprotective fraction of Hypericum perforatum, Int J Biol Macromol 110: 185-196, doi: 10.1016/j.ijbiomac.2017.10.103

Sousa F, Cruz A, Fonte P, Pinto IM, Neves-Petersen MT, Sarmento B (2017) A new paradigm for antiangiogenic therapy through controlled release of bevacizumab from PLGA nanoparticles, Sci Rep 7(1): 3736, doi: 10.1038/s41598-017-03959-4

Fonte P, Andrade F, Azevedo C, Pinto J, Seabra V, van de Weert M, Reis S, Sarmento B (2016) Effect of the freezing step in the stability and bioactivity of protein-loaded PLGA nanoparticles upon lyophilization, Pharm Res 33(11): 2777–2793, doi: 10.1007/s11095-016-2004-3

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