Nuno P. Mira

Assistant Professor

Research Activities

Current research interests are focused on: i) Physiology and molecular biology of Candida glabrata, Saccharomyces cerevisiae and Zygosaccharomyces bailii; ii) Regulation of gene and genomic expression in C. glabrata and S. cerevisiae under environmental stress; iii) Exploitation of S. cerevisae as a cell factory for the production of add-value chemicals; iv) Molecular mechanisms of pathogenesis in C. glabrata; v) Epidemiology of invasive fungal infections; vi) Development of molecular-based diagnosis tools for the early detection of invasive fungal infections

Selected Publications

Nuno P. Mira, Sílvia Henriques, Greg Keller, Miguel C. Teixeira, Rute G. Matos, Cecília M. Arraiano, Dennis R. Winge and Isabel Sá-Correia, “Identification of a DNA binding site for the transcription factor Haa1p, required for Saccharomyces cerevisiae response to acetic acid stress”, Nucleic Acids Research, 16, 6896-907, (2011)

Mira NP, Teixeira MC and Sá-Correia I, “Adaptation and resistance to weak acids in Saccharomyces cerevisiae: a genome-wide view”, OMICS: a Journal of Integrative Biology, 14:5, 525-40, (2010)

Mira NP, Palma M, Guerreiro JF and Sá-Correia I, Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid, Microbial Cell Factories, 9:79, (2010)

Guerreiro JF, Mira NP and Sá-Correia I, Adaptive response to acetic acid in the highly resistant species Zygosaccharomyces bailii revealed by quantitative proteomics, Proteomics, 12(14): 2303-18, (2012)

Teixeira MC, Mira NP and Isabel Sá-Correia, “A genome-wide perspective on food-relevant stress responses in yeast”, Current Opinion in Biotechnology, 22:150-6, (2011)

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