Marília Mateus

Assistant professor

Research Activities

Application of synthetic membranes to bioengineering fields, entailing processing (crossflow filtration and chromatography), surface modification (for biocompatibility, filtration improvement and selective adsorption capacity), and bioreactors. Interest in bioprocess integration regarding microbial cell factories for the production of biofarmaceuticals.

Selected Publications

Monteiro, M.E., Raiado-Pereira, L., Prazeres, D.M.F., Mateus, M., “Preparation of liposome membrane adsorbers and testing for plasmid purification”, Biochem. Eng. J. 93, 1-10 (2015). doi:10.1016/j.bej.2014.09.005

Nascimento, A., Rosa, S.A.S.L., Mateus, M., Azevedo, A.M., “Polishing of monoclonal antibodies streams through convective flow devices”, Sep. Purif. Technol. 132, 593-600 (2014). doi:10.1016/j.seppur.2014.06.005

Raiado-Pereira, L., Vega, J.D.L., Prazeres, D.M.F., Mateus, M., "Development of a phenyl membrane chromatography-based process yielding pharmaceutical grade plasmid deoxyribonucleic acid for mammalian cells transfection", J. Chromatogr. A 1337, 67-74 (2014). doi:10.1016/j.chroma.2014.02.024

Raiado-Pereira, L., Prazeres, D.M.F., Mateus, M., “Impact of plasmid size on the purification of model plasmid DNA vaccines by phenyl membrane adsorbers”, J. Chromatogr. A 1315, 145-15 (2013). doi:10.1016/j.chroma.2013.09.076

Raiado-Pereira, L., Carapeto, A.P., Botelho-do-Rego, A.M., Mateus, M., "Grafting hydrophobic and affinity interaction ligands on membrane adsorbers: A close-up ‘‘view’’ by X-ray photoelectron spectroscopy", Sep. Purif. Technol. 93, 75-82 (2012). doi: 10.1016/j.seppur.2012.03.028

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