Isabel Sá-Correia
IST  Distinguished Full Professor

Research Activities

Isabel Sá-Correia research interests are in the fields of Molecular and Cellular Microbiology, Microbial Biotechnology, and Functional and Comparative Genomics and Bioinformatics. Research strategies explore the interface between “Omic” analyses, (transcriptomics, proteomics, chemogenomics, metabolomics, lipidomics) and molecular and cellular microbiology research to characterize new regulatory pathways under stress, to obtain mechanistic insights, a genome-wide view, and a systems-based understanding of the responses of yeasts and gram-negative bacteria to environmental challenges relevant to improve/control their activity in Industrial and Agro-Food, Health, and Environmental Biotechnology. (Read more)

Selected Publications

Antunes, M., Palma, M., Sa-Correia, I., Transcriptional profiling of Zygosaccharomyces bailii early response to acetic acid or copper stress mediated by ZbHaa1, Scientific Reports   Volume: 8 , Article Number: 14122, 2018

Godinho, Claudia P.; Prata, Catarina S.; Pinto, Sandra N., Cardoso, C, Bandarra, NM, Fernandes, F , Sa-Correia, I, Pdr18 is involved in yeast response to acetic acid stress counteracting the decrease of plasma membrane ergosterol content and order, Scientific Reports ,  Volume: 8,     Article Number: 7860, 2018

Hassan AA, Maldonado RF, Dos Santos SC, Di Lorenzo F, Silipo A, Coutinho CP, Cooper VS, Molinaro A, Valvano MA, Sá-Correia I. “Structure of O-Antigen and Hybrid Biosynthetic Locus in Burkholderia cenocepacia Clonal Variants Recovered from a Cystic Fibrosis Patient", Frontiers in Microbiology, 8:1027, 2017.

Henriques, S.F., Mira, N.P., Sá-Correia, I., “Genome-wide search for candidate genes for yeast robustness improvement against formic acid reveals novel susceptibility (Trk1 and positive regulators) and resistance (Haa1-regulon) determinants”, Biotechnology and Biofuels, 10: 96, 2017.

Teixeira, M.C., Monteiro, P.T., Palma, M., Catarina, C., Godinho, C.P., Pais, P., Cavalheiro, M., Antunes, M., Lemos, A., Pedreira, T., Sá-Correia, I. YEASTRACT, an upgraded database for the analysis of transcription regulatory networks in Saccharomyces cerevisiae", Nucleic Acids Research, DataBase Issue Jan 2018, in press


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