Gabriel A. Monteiro

Associate Professor

Research Activities

My research is focused on the design and manufacturing of plasmid and minicircles biopharmaceuticals, to be used as DNA vaccines and gene therapy vectors for transient cell modification.

Selected Publications

De la Vega J, Monteiro GA, Prazeres DMF (2016) Use of DNA stabilizers to extend plasmid biological activity, Curr. Bionanotec. 1, 102-109, doi:10.2174/2213529402666151214222447

Šimčíková M, Prather KLJ, Prazeres DMF, Monteiro GA (2016) Towards effective non-viral gene delivery vector, Biotechnol. Genet. Eng. Rev. 31: 82-107, doi:10.1080/02648725.2016.1178011

Alves CPA, Šimčíková M, Prather KLJ, Monteiro GA, Prazeres DMF. (2016) Development of a nicking endonuclease-assisted method for the purification of minicircles, J. Chromatogr. A 1443, 136-144, doi:10.1016/j.chroma.2016.03.035

Matos JC, Soares AR, Domingues I, Monteiro GA, Gonçalves MC (2016) ORMOPLEXEs for gene therapy: in vitro and in vivo assays, Mater. Sci. Eng. C 63, 546-553, doi:10.1016/j.msec.2016.03.006

Šimčíková M, Alves CPA, Brito L, Prather KLJ, Prazeres DMF, Monteiro GA (2016) Improvement of DNA minicircle production by optimization of the secondary structure of the 5'-UTR of ParA resolvase, Appl. Microb. Biot. 100: 6725-6737, doi:10.1007/s00253-016-7565-x

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