Dalila Madeira Nascimento Mil-Homens

Post-Doctoral research fellow

Research Activities

My research interests are focused on studying surface exposed proteins, namely trimeric autotransporter adhesins (TAAs), in Burkholderia cenocepacia pathogenicity associated with infection of the human respiratory tract. Beside the functional characterization of TAAs the main line of research are the interactions with the host airway epithelial cells and immune system. Galleria mellonella wax moth larva is our model host for examining B. cenocepacia virulence.

Selected Publications

El-Kirat-Chatel S, Mil-Homens D, Beaussart A, Fialho AM, Dufrêne YF (2013). Single-molecule atomic force microscopy unravels the binding mechanism of a Burkholderia cenocepacia trimeric autotransporter adhesin. Molecular Microbiology. doi: 10.1111/mmi.12301.

Mil-Homens D, Fialho AM (2012). A BCAM0223 mutant of Burkholderia cenocepacia K56-2 is deficient in hemagglutination and exhibits impaired serum resistance and adhesion to epithelial cells. PlosONE, 7(7):e41747.

Mil-Homens D, Bernardes N, Fialho AM (2012). The antibacterial properties of docosahexaenoic omega-3 fatty acid against the Cystic Fibrosis multi-resistant pathogen Burkholderia cenocepacia. FEMS Microbiology Letters 328(1): 61-69.

Mil-Homens D, Fialho AM. (2011). Trimeric autotransporter adhesins in members of the Burkholderia cepacia complex: a multifunctional family of proteins implicated in virulence. Frontiers in Cellular and Infection Microbiology 1:13. doi: 10.3389/fcimb.2011.00013.

Mil-Homens D, Rocha EPC, Fialho AM (2010). Genome-wide analysis of DNA repeats in Burkholderia cenocepacia J2315 identifies a novel adhesin-like gene unique to epidemic-associated strains of the ET-12 lineage. Microbiology 156(4): 1084-1096.

E-mail (click on)