Ana Catarina Portinha e Costa

Post-Doctoral research fellow


Research Activities

- Mechanisms of antifungal drug resistance in the human pathogen Candida glabrata
- Microbial physiology and molecular biology
- Chemogenomics and expression proteomics.

 

Selected Publications

 

Monteiro, P.T., Pais, P., Costa, C., Manna, S., Sá-Correia, I., Teixeira, M.C., 2017, "The PathoYeastract database: an information system for the analysis of gene and genomic transcription regulation in pathogenic yeasts", Nucleic Acids Research, DOI: 10.1093/nar/gkw817.

 

Costa, C., Ribeiro, J., Miranda, I.M., Silva-Dias, A.I., Cavalheiro, M., Costa-de-Oliveira, S., Rodrigues, A.G., Teixeira, M.C., "Clotrimazole drug resistance in Candida glabrata clinical isolates correlates with increased expression of the drug:H+ antiporters CgAqr1, CgTpo1_1, CgTpo3 and CgQdr2", Frontiers in Microbiology, 7:256, 2016.

 

Pais, P., Costa, C., Pires, C., Shimizu, K., Chibana, H., Teixeira, M.C., “Membrane proteome-wide response to the antifungal drug clotrimazole in Candida glabrata: role of the transcription factor CgPdr1 and the Drug:H+ Antiporters CgTpo1_1 and CgTpo1_2”, Molecular and Cellular Proteomics, 15(1):57-72, 2016.

 

Costa, C., Nunes, J., Henriques, A., Mira, N.P., Nakayama, H., Chibana, H., Teixeira, M.C., "The Candida glabrata drug:H+ antiporter CgTpo3 (ORF CAGL0I10384g): role in azole drug resistance and polyamine homeostasis", Journal of Antimicrobial Chemotherapy, 69:1767-76, 2014.

 

Costa, C., Pires, C., Cabrito, T.R., Renaudin, A., Ohno, M., Chibana, H., Sá-Correia, I., Teixeira, M.C., "Candida glabrata drug:H+ antiporter CgQdr2 (ORF CAGL0G08624g) confers imidazole drug resistance, being activated by the CgPdr1 transcription factor", Antimicrobial Agents and Chemotherapy, 57(7):3159-67, 2013.

 

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